elsamitrucin

{
  "id": "MLC-T-ONC-013312",
  "term": "elsamitrucin",
  "field": "Oncology and biomedicine",
  "definition": "A heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits topoisomerase I and II, resulting in single-strand breaks and inhibition of DNA replication.",
  "synonyms": [
    "elsamicin A",
    "10-O-elsaminosylelsarosylchartarin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/elsamitrucin/"
}