Echinomycin
Term · Oncology and biomedicine · MLC-T-ONC-013203
A polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis.
| Identifier | MLC-T-ONC-013203 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | bis-quinoline analogue; echinomycin A; levomycin; quinomycin A |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013203",
"term": "Echinomycin",
"field": "Oncology and biomedicine",
"definition": "A polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis.",
"synonyms": [
"bis-quinoline analogue",
"echinomycin A",
"levomycin",
"quinomycin A"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/echinomycin/"
}
Record 6,351 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.