MLchartDataset catalogue

Echinomycin

Term · Oncology and biomedicine · MLC-T-ONC-013203

A polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis.

Table 1. Record
IdentifierMLC-T-ONC-013203
FieldOncology and biomedicine
Synonymsbis-quinoline analogue; echinomycin A; levomycin; quinomycin A
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013203",
  "term": "Echinomycin",
  "field": "Oncology and biomedicine",
  "definition": "A polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis.",
  "synonyms": [
    "bis-quinoline analogue",
    "echinomycin A",
    "levomycin",
    "quinomycin A"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/echinomycin/"
}

Record 6,351 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.