MLchartDataset catalogue

CDKN2A gene

Term · Oncology and biomedicine · MLC-T-ONC-001540

A gene that makes two major proteins involved in controlling cell growth, cell division, and a type of cell death called apoptosis. Mutations (changes) in the CDKN2A gene may cause cells to grow and divide too quickly or in an uncontrolled way or may keep cells from undergoing apoptosis. This may cause abnormal cells, including cancer cells, to grow. CDKN2A gene mutations have been found in melanoma and in many other types of cancer. The CDKN2A gene is a type of tumor suppressor gene.

Table 1. Record
IdentifierMLC-T-ONC-001540
FieldOncology and biomedicine
ReferencesNCI Dictionary of Cancer Terms
Record as JSON
{
  "id": "MLC-T-ONC-001540",
  "term": "CDKN2A gene",
  "field": "Oncology and biomedicine",
  "definition": "A gene that makes two major proteins involved in controlling cell growth, cell division, and a type of cell death called apoptosis. Mutations (changes) in the CDKN2A gene may cause cells to grow and divide too quickly or in an uncontrolled way or may keep cells from undergoing apoptosis. This may cause abnormal cells, including cancer cells, to grow. CDKN2A gene mutations have been found in melanoma and in many other types of cancer. The CDKN2A gene is a type of tumor suppressor gene.",
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/cdkn2a-gene/"
}

Record 4,512 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.