MLchartDataset catalogue

clavulanic acid

Term · Oncology and biomedicine · MLC-T-ONC-012630

A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This agent is used in conjunction with beta-lactamase susceptible antibiotics, such as penicillins and cephalosporins, to treat infections caused by beta-lactamase producing organisms.

Table 1. Record
IdentifierMLC-T-ONC-012630
FieldOncology and biomedicine
Synonymsantibiotic MM 14151
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-012630",
  "term": "clavulanic acid",
  "field": "Oncology and biomedicine",
  "definition": "A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This agent is used in conjunction with beta-lactamase susceptible antibiotics, such as penicillins and cephalosporins, to treat infections caused by beta-lactamase producing organisms.",
  "synonyms": [
    "antibiotic MM 14151"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/clavulanic-acid/"
}

Record 4,929 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.