clavulanic acid
Term · Oncology and biomedicine · MLC-T-ONC-012630
A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This agent is used in conjunction with beta-lactamase susceptible antibiotics, such as penicillins and cephalosporins, to treat infections caused by beta-lactamase producing organisms.
| Identifier | MLC-T-ONC-012630 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | antibiotic MM 14151 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012630",
"term": "clavulanic acid",
"field": "Oncology and biomedicine",
"definition": "A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This agent is used in conjunction with beta-lactamase susceptible antibiotics, such as penicillins and cephalosporins, to treat infections caused by beta-lactamase producing organisms.",
"synonyms": [
"antibiotic MM 14151"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/clavulanic-acid/"
}
Record 4,929 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.