novobiocin

{
  "id": "MLC-T-ONC-005942",
  "term": "novobiocin",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An antibiotic drug used to treat infection.",
    "An aminocoumarin antibiotic, produced by the actinomycete Streptomyces nivens, with antibacterial property. Novobiocin, as well as other aminocoumarin antibiotics, inhibits bacterial DNA synthesis by targeting at the bacteria DNA gyrase and the related enzyme DNA topoisomerase IV. This antibiotic was used to treat infections by gram-positive bacteria."
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/novobiocin/"
}