cilengitide

{
  "id": "MLC-T-ONC-001766",
  "term": "cilengitide",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A substance that is being studied as an anticancer and antiangiogenesis drug. Also called EMD 121974.",
    "A cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis."
  ],
  "abbreviation": "EMD 121974",
  "synonyms": [
    "EMD 121974"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cilengitide/"
}