Integrin alpha-2 inhibitor E7820

{
  "id": "MLC-T-ONC-014469",
  "term": "Integrin alpha-2 inhibitor E7820",
  "field": "Oncology and biomedicine",
  "definition": "A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/integrin-alpha-2-inhibitor-e7820/"
}