Fluorine F 18 integrin alpha v beta 6-targeted binding peptide

{
  "id": "MLC-T-ONC-013686",
  "term": "Fluorine F 18 integrin alpha v beta 6-targeted binding peptide",
  "field": "Oncology and biomedicine",
  "definition": "A radiotracer composed of an integrin alphaVbeta6 (aVb6) binding peptide (BP) radiolabeled with the radionuclide fluorine F 18, with potential integrin aVb6 imaging activity using positron emission tomography (PET). Upon administration, the fluorine F 18 integrin aVb6-targeted peptide selectively binds to integrin aVb6-positive cancer cells. During PET, aVb6-expressing tumor cells can be visualized and the degree of tumor growth can be determined. Integrin aVb6, a cell adhesion and signaling receptor, is upregulated in certain cancer cell types and has been associated with increased proliferation, migration and invasion of tumor cells.",
  "abbreviation": "18F-αvβ6-BP",
  "synonyms": [
    "18F-aVb6-binding-peptide",
    "18F-alphavbeta6-binding peptide"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-integrin-alpha-v-beta-6-targeted-binding-peptide/"
}