MLchartDataset catalogue

fluorine F 18 GEH121224

Term · Oncology and biomedicine · MLC-T-ONC-013685

A radioconjugate composed of a human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2)-targeting ligand labeled with the radioisotope fluorine F 18, with potential use as a tracer for HER2-expressing tumors during positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 GEH121224, the HER2-targeting moiety targets and binds to HER2-expressing tumor cells. Upon binding, HER2-expressing tumor cells can be detected during PET/CT imaging. HER2, a tumor-associated antigen (TAA) overexpressed on a variety of tumor cell types, plays an important role in tumor cell proliferation, differentiation and survival.

Table 1. Record
IdentifierMLC-T-ONC-013685
FieldOncology and biomedicine
Synonyms18F-GEH121224; [18F]-GEH121224; [18F]GEH121224; fluorine F 18-labeled GEH121224; GEH121224 (18F)
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013685",
  "term": "fluorine F 18 GEH121224",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of a human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2)-targeting ligand labeled with the radioisotope fluorine F 18, with potential use as a tracer for HER2-expressing tumors during positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 GEH121224, the HER2-targeting moiety targets and binds to HER2-expressing tumor cells. Upon binding, HER2-expressing tumor cells can be detected during PET/CT imaging. HER2, a tumor-associated antigen (TAA) overexpressed on a variety of tumor cell types, plays an important role in tumor cell proliferation, differentiation and survival.",
  "synonyms": [
    "18F-GEH121224",
    "[18F]-GEH121224",
    "[18F]GEH121224",
    "fluorine F 18-labeled GEH121224",
    "GEH121224 (18F)"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-geh121224/"
}

Record 7,435 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.