fluorine F 18 GEH121224
Term · Oncology and biomedicine · MLC-T-ONC-013685
A radioconjugate composed of a human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2)-targeting ligand labeled with the radioisotope fluorine F 18, with potential use as a tracer for HER2-expressing tumors during positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 GEH121224, the HER2-targeting moiety targets and binds to HER2-expressing tumor cells. Upon binding, HER2-expressing tumor cells can be detected during PET/CT imaging. HER2, a tumor-associated antigen (TAA) overexpressed on a variety of tumor cell types, plays an important role in tumor cell proliferation, differentiation and survival.
| Identifier | MLC-T-ONC-013685 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | 18F-GEH121224; [18F]-GEH121224; [18F]GEH121224; fluorine F 18-labeled GEH121224; GEH121224 (18F) |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013685",
"term": "fluorine F 18 GEH121224",
"field": "Oncology and biomedicine",
"definition": "A radioconjugate composed of a human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2)-targeting ligand labeled with the radioisotope fluorine F 18, with potential use as a tracer for HER2-expressing tumors during positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 GEH121224, the HER2-targeting moiety targets and binds to HER2-expressing tumor cells. Upon binding, HER2-expressing tumor cells can be detected during PET/CT imaging. HER2, a tumor-associated antigen (TAA) overexpressed on a variety of tumor cell types, plays an important role in tumor cell proliferation, differentiation and survival.",
"synonyms": [
"18F-GEH121224",
"[18F]-GEH121224",
"[18F]GEH121224",
"fluorine F 18-labeled GEH121224",
"GEH121224 (18F)"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/fluorine-f-18-geh121224/"
}
Record 7,435 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.