fluorine F 18 florastamin

{
  "id": "MLC-T-ONC-013672",
  "term": "fluorine F 18 florastamin",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of the human prostate-specific membrane antigen (PSMA)-targeting ligand, florastamin, labeled with the radioisotope fluorine F 18, with potential use as a tracer for PSMA-expressing tumors during positron emission tomography/computed tomography (PET/CT). Upon administration of fluorine F 18 florastamin, the florastamin moiety targets and binds to PSMA-expressing tumor cells. Upon binding, PSMA-expressing tumor cells can be detected during PET/CT imaging. PSMA, a tumor-associated antigen (TAA) and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate tumor cells.",
  "synonyms": [
    "18F-florastamin",
    "[18F]-florastamin",
    "[F-18] florastamin",
    "fluorine-18 florastamin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-florastamin/"
}