MLchartDataset catalogue

fluorine F 18 piflufolastat

Term · Oncology and biomedicine · MLC-T-ONC-013693

A urea-based radiotracer composed of the prostate specific membrane antigen (PSMA) targeting agent DCFPyL and labeled with the positron-emitting isotope, fluorine F 18, that can potentially be used for positron emitting tomography (PET) imaging. Upon administration of fluorine F piflufolastat, piflufolastat binds to PSMA expressed on tumor cells. The fluorine F 18 moiety facilitates PET imaging of PSMA-expressing tumor cells. PSMA, a cell-surface antigen, is abundantly present on the surface of prostate cancer cells and on the neovasculature of most solid tumors.

Table 1. Record
IdentifierMLC-T-ONC-013693
FieldOncology and biomedicine
Abbreviation18F-DCFPyL
Synonymsfluorine F 18 DCFPyL; piflufolastat F 18; piflufolastat F-18; piflufolastat F18
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013693",
  "term": "fluorine F 18 piflufolastat",
  "field": "Oncology and biomedicine",
  "definition": "A urea-based radiotracer composed of the prostate specific membrane antigen (PSMA) targeting agent DCFPyL and labeled with the positron-emitting isotope, fluorine F 18, that can potentially be used for positron emitting tomography (PET) imaging. Upon administration of fluorine F piflufolastat, piflufolastat binds to PSMA expressed on tumor cells. The fluorine F 18 moiety facilitates PET imaging of PSMA-expressing tumor cells. PSMA, a cell-surface antigen, is abundantly present on the surface of prostate cancer cells and on the neovasculature of most solid tumors.",
  "abbreviation": "18F-DCFPyL",
  "synonyms": [
    "fluorine F 18 DCFPyL",
    "piflufolastat F 18",
    "piflufolastat F-18",
    "piflufolastat F18"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-piflufolastat/"
}

Record 7,443 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.