fluorine F 18 piflufolastat
Term · Oncology and biomedicine · MLC-T-ONC-013693
A urea-based radiotracer composed of the prostate specific membrane antigen (PSMA) targeting agent DCFPyL and labeled with the positron-emitting isotope, fluorine F 18, that can potentially be used for positron emitting tomography (PET) imaging. Upon administration of fluorine F piflufolastat, piflufolastat binds to PSMA expressed on tumor cells. The fluorine F 18 moiety facilitates PET imaging of PSMA-expressing tumor cells. PSMA, a cell-surface antigen, is abundantly present on the surface of prostate cancer cells and on the neovasculature of most solid tumors.
| Identifier | MLC-T-ONC-013693 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | 18F-DCFPyL |
| Synonyms | fluorine F 18 DCFPyL; piflufolastat F 18; piflufolastat F-18; piflufolastat F18 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013693",
"term": "fluorine F 18 piflufolastat",
"field": "Oncology and biomedicine",
"definition": "A urea-based radiotracer composed of the prostate specific membrane antigen (PSMA) targeting agent DCFPyL and labeled with the positron-emitting isotope, fluorine F 18, that can potentially be used for positron emitting tomography (PET) imaging. Upon administration of fluorine F piflufolastat, piflufolastat binds to PSMA expressed on tumor cells. The fluorine F 18 moiety facilitates PET imaging of PSMA-expressing tumor cells. PSMA, a cell-surface antigen, is abundantly present on the surface of prostate cancer cells and on the neovasculature of most solid tumors.",
"abbreviation": "18F-DCFPyL",
"synonyms": [
"fluorine F 18 DCFPyL",
"piflufolastat F 18",
"piflufolastat F-18",
"piflufolastat F18"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/fluorine-f-18-piflufolastat/"
}
Record 7,443 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.