MLchartDataset catalogue

fluorine F 18 CP18 peptide

Term · Oncology and biomedicine · MLC-T-ONC-013663

A triazole containing pentapeptide labeled with the positron-emitting isotope fluorine F 18, used as a tracer for positron emitting tomography (PET) imaging. As a caspase-3 specific substrate, fluorine F 18 CP18 peptide is preferentially taken up by and accumulates in tumor cells with high caspase-3 activity. Upon PET imaging, apoptotic cells can be detected and apoptotic activity can be assessed. Caspase-3 is a cysteine protease that plays a key role in the induction of apoptosis.

Table 1. Record
IdentifierMLC-T-ONC-013663
FieldOncology and biomedicine
Synonyms18F-CP18 peptide; [F18]CP-18 peptide
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013663",
  "term": "fluorine F 18 CP18 peptide",
  "field": "Oncology and biomedicine",
  "definition": "A triazole containing pentapeptide labeled with the positron-emitting isotope fluorine F 18, used as a tracer for positron emitting tomography (PET) imaging. As a caspase-3 specific substrate, fluorine F 18 CP18 peptide is preferentially taken up by and accumulates in tumor cells with high caspase-3 activity. Upon PET imaging, apoptotic cells can be detected and apoptotic activity can be assessed. Caspase-3 is a cysteine protease that plays a key role in the induction of apoptosis.",
  "synonyms": [
    "18F-CP18 peptide",
    "[F18]CP-18 peptide"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-cp18-peptide/"
}

Record 7,413 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.