fluorine F 18 CP18 peptide
Term · Oncology and biomedicine · MLC-T-ONC-013663
A triazole containing pentapeptide labeled with the positron-emitting isotope fluorine F 18, used as a tracer for positron emitting tomography (PET) imaging. As a caspase-3 specific substrate, fluorine F 18 CP18 peptide is preferentially taken up by and accumulates in tumor cells with high caspase-3 activity. Upon PET imaging, apoptotic cells can be detected and apoptotic activity can be assessed. Caspase-3 is a cysteine protease that plays a key role in the induction of apoptosis.
| Identifier | MLC-T-ONC-013663 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | 18F-CP18 peptide; [F18]CP-18 peptide |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013663",
"term": "fluorine F 18 CP18 peptide",
"field": "Oncology and biomedicine",
"definition": "A triazole containing pentapeptide labeled with the positron-emitting isotope fluorine F 18, used as a tracer for positron emitting tomography (PET) imaging. As a caspase-3 specific substrate, fluorine F 18 CP18 peptide is preferentially taken up by and accumulates in tumor cells with high caspase-3 activity. Upon PET imaging, apoptotic cells can be detected and apoptotic activity can be assessed. Caspase-3 is a cysteine protease that plays a key role in the induction of apoptosis.",
"synonyms": [
"18F-CP18 peptide",
"[F18]CP-18 peptide"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/fluorine-f-18-cp18-peptide/"
}
Record 7,413 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.