Fluorine F 18-labeled 2-FACPC

{
  "id": "MLC-T-ONC-013719",
  "term": "Fluorine F 18-labeled 2-FACPC",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of an analog of the synthetic, alicyclic amino acid aminocyclopentane carboxylic acid (ACPC) radiolabeled with the positron-emitting isotope fluorine F 18 (2-[18F]FACPC), with potential cancer cell imaging activity during positron emission tomography (PET). As tumor cells have a higher rate of protein synthesis than normal, healthy cells, upon administration, fluorine F 18 labeled 2-FACPC is selectively taken up by rapidly proliferating tumor cells through the sodium-independent subtype L amino acid transport system (AAT) which leads to the accumulation of this tracer in tumor cells. Upon PET, tumor cells can then be visualized.",
  "synonyms": [
    "2-[(18)F]FACPC",
    "2-[18F]FACPC",
    "anti-1-amino-2-[18F]fluorocyclopentyl-1-carboxylic acid",
    "anti-2-[(18)F]FACPC"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-labeled-2-facpc/"
}