Fluorine F 18-labeled DX600

{
  "id": "MLC-T-ONC-013720",
  "term": "Fluorine F 18-labeled DX600",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate composed of DX600, a peptide targeting angiotensin converting enzyme 2 (ACE2), labeled with the radioisotope fluorine F 18, with potential imaging activity upon positron emission tomography (PET). Upon administration of fluorine F 18-labeled DX600, DX600 targets and binds to ACE2. Upon PET imaging, ACE2 expression can be assessed. ACE2 plays an important role in the renin-angiotensin system (RAS), and may be overexpressed in tumors.",
  "synonyms": [
    "18F-labeled DX600",
    "fluorine F 18-ACE2 inhibitor DX600",
    "18F-DX600"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-labeled-dx600/"
}