fluorine F 18-PEG3-FPN

{
  "id": "MLC-T-ONC-013723",
  "term": "fluorine F 18-PEG3-FPN",
  "field": "Oncology and biomedicine",
  "definition": "A radioconjugate comprised of PEG3-FPN, a pegylated tracer for melanin, and labeled with the positron-emitting isotope fluorine F 18, that can be used as a diagnostic imaging agent to detect melanin-expressing cells using positron emission tomography (PET). Upon administration, fluorine F 18-PEG3-FPN targets and binds to melanin-expressing cells. Upon PET, fluorine F 18 can be detected, and melanin-expressing cells can be visualized. Melanin is expressed in many melanomas, and pegylation lowers nonspecific uptake by the liver.",
  "synonyms": [
    "18F-PEG3-FPN"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/fluorine-f-18-peg3-fpn/"
}