TLR9 agonist EMD 1201081

{
  "id": "MLC-T-ONC-017210",
  "term": "TLR9 agonist EMD 1201081",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic oligonucleotide containing phosphorothioate oligodeoxynucleotide with potential immunopotentiating activity. TLR9 agonist EMD 1201081 binds to and activates the intracellular Toll-like receptor (TLR) 9 in monocytes/macrophages, plasmacytoid dendritic cells (DCs) and B cells, initiating immune signaling pathways, activating B cells and inducing T-helper cell cytokine production. TLR9 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity.",
  "synonyms": [
    "Toll-like receptor 9 agonist EMD 1201081"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/tlr9-agonist-emd-1201081/"
}