Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: U (164)

• UAE inhibitor TAK-243A small molecule inhibitor of ubiquitin-activating enzyme (UAE), with potential antineoplastic activity. UAE...
• ubamatamabA bispecific, human monoclonal antibody with potential antineoplastic activity. REGN4018 contains two...
• ubavitinib tosylateThe tosylate salt form of NB003, an orally bioavailable inhibitor of specific mutated forms of...
• ubidecarenone nanodispersion BPM31510A nanodispersion containing the benzoquinone ubidecarenone (coenzyme Q10), with potential protective...
• ubiquinoneA nutrient that the body needs in small amounts to function and stay healthy. Ubiquinone helps mitochondria...
• ublituximabA chimeric recombinant IgG1 monoclonal antibody directed against human CD20 with potential antineoplastic...
• UCN-01An anticancer drug that belongs to the family of drugs called staurosporine analogs.
• udenafilA benzenesulfonamide derivative with vasodilatory activity. Udenafil selectively inhibits phosphodiesterase...
• UdenycaA drug that is a form of filgrastim and is used to prevent infection in adults and children with neutropenia...
• UFTA substance being studied in the treatment of some types of cancer. It is a combination of tegafur and...
• UGT1A1A substance that is being studied as a treatment for cancer. It is an enzyme produced by the liver and...
• ulcerA break on the skin, in the lining of an organ, or on the surface of a tissue. An ulcer forms when the...
• ulcerationThe formation of a break on the skin or on the surface of an organ. An ulcer forms when the surface cells die...
• ulcerative colitisChronic inflammation of the colon that produces ulcers in its lining. This condition is marked by abdominal...
• ulimorelin hydrochlorideThe hydrochloride salt form of ulimorelin, a macrocyclic ghrelin peptidomimetic, with potential...
• ulinastatinA multivalent Kunitz-type serine protease inhibitor derived from human urine, with potential protective...
• ulipristal acetateAn orally bioavailable, acetate ester of ulipristal, a selective progesterone receptor modulator with...
• ulixertinibAn orally available inhibitor of extracellular signal-regulated kinase (ERK) 1 and 2, with potential...
• ULK1/2 inhibitor DCC-3116An orally bioavailable inhibitor of the serine/threonine-protein kinase ULK 1 and 2, with potential...
• Ulmus fulvaThe inner bark of this plant has been used in some cultures to treat certain medical problems. It may have...
• Ulmus rubraThe inner bark of this plant has been used in some cultures to treat certain medical problems. It may have...
• ulocuplumabAn orally bioavailable monoclonal antibody against CXC chemokine receptor 4 (CXCR4) with potential...
• UltomirisA drug used to treat adults with paroxysmal nocturnal hemoglobinuria (a rare red blood cell disorder) and...
• ultra light cigaretteA type of cigarette that is claimed to give off less tobacco tar than a regular or light (“low-tar”)...
• UltramA drug used to treat moderate to severe pain in adults. It binds to opioid receptors in the central nervous...
• ultra-micronized palmitoyl ethylamine (PEA) FSD-201An orally bioavailable, ultra-micronized formulation of the fatty acid amide palmitoyl ethylamine (PEA), with...
• ultrasonogramA computer picture of areas inside the body created by high-energy sound waves. The sound waves are bounced...
• ultrasonographyA procedure that uses high-energy sound waves to look at tissues and organs inside the body. The sound waves...
• ultrasoundA procedure that uses high-energy sound waves to look at tissues and organs inside the body. The sound waves...
• ultrasound biomicroscopyA type of ultrasound eye exam that makes a more detailed image than regular ultrasound. High-energy sound...
• ultrasound energyA form of therapy being studied as an anticancer treatment. Intensified ultrasound energy can be directed at...
• ultrasound transducerA device that produces sound waves that bounce off body tissues and make echoes. The transducer also receives...
• ultrasound-guided biopsyA biopsy procedure that uses an ultrasound imaging device to find an abnormal area of tissue and guide its...
• ultraviolet A radiationInvisible rays that are part of the energy that comes from the sun. Ultraviolet A radiation also comes from...
• ultraviolet B radiationInvisible rays that are part of the energy that comes from the sun. Ultraviolet B radiation causes sunburn...
• ultraviolet C radiationInvisible rays that are part of the energy that comes from the sun. Most ultraviolet C radiation from the sun...
• ultraviolet radiationInvisible rays that are part of the energy that comes from the sun. Ultraviolet radiation that reaches the...
• ultraviolet radiation therapyA form of radiation used in the treatment of cancer.
• ulviprubartA humanized, afucosylated monoclonal antibody directed against killer cell lectin-like receptor G1 (KLRG1)...
• umbilical cord bloodBlood from the umbilical cord of a newborn baby. This blood contains high concentrations of stem cells (cells...
• umbilical cord blood transplantationThe injection of umbilical cord blood to restore an individual's own blood production system suppressed by...
• umbilical cord blood-derived CD16-expressing natural killer cells AB-101A preparation of allogeneic, off-the-shelf natural killer (NK) cells, derived from umbilical cord blood (UCB)...
• umbilical cord blood-derived CD4+/CD25+ T-regulatory cells CK0801A preparation composed of allogeneic umbilical cord blood (UCB)-derived, ex vivo expanded and enhanced...
• umbilical cord blood-derived MAK immune cellsA preparation of mixed-activated killer (MAK) immune cells derived from human umbilical cord blood (UCB)...
• umbilical cord blood-derived mesenchymal stem cellsMultipotent stem cells of mesenchymal origin isolated from umbilical cord blood. Umbilical cord blood-derived...
• umbilical cord blood-derived natural killer cellsA population of allogeneic, cytokine-differentiated, highly lytic natural killer (NK) cells derived from...
• umbralisib tosylateThe tosylate form of umbralisib, an orally bioavailable, selective inhibitor of the delta isoform of the 110...
• umbrella trialA type of clinical trial that tests how well new drugs or other substances work in patients who have the same...
• unaffected individualIn genetics, a term used to describe a person who does not have a certain genetic trait or disease.
• Uncaria tomentosa extractAn extract of Uncaria tomentosa (U. tomentosa), also called Cat's claw, a native Amazonian plant belonging to...
• unclassified sarcomaA group of rare cancers that do not look like other types of sarcomas under a microscope and may be hard to...
• unclassified variantA change in a gene’s DNA sequence that has an unknown effect on a person’s health. There is usually not...
• uncontrolled studyA clinical study that lacks a comparison (i.e., a control) group.
• unconventional cancer treatmentsApproaches that use substances or methods of treating cancer that have not been shown to be effective by...
• underactive thyroidToo little thyroid hormone. Symptoms include weight gain, constipation, dry skin, and sensitivity to the...
• undescended testiclesA condition in which one or both testicles fail to move from the abdomen, where they develop before birth...
• undifferentiatedA term used to describe cells or tissues that do not have specialized ("mature") structures or functions...
• undifferentiated pleomorphic sarcomaA type of cancer that usually forms in the soft tissue, but it may also form in bone. It can occur anywhere...
• undifferentiated sarcomaA group of rare cancers that do not look like other types of sarcomas under a microscope and may be hard to...
• unesbulinAn orally active inhibitor of the polycomb ring finger oncogene BMI1 (B-cell-specific Moloney murine leukemia...
• unguentA substance used on the skin to soothe or heal wounds, burns, rashes, scrapes, or other skin problems. Also...
• uniformly-labeled [13C]fructoseA uniformly-labeled radioconjugate composed of the monosaccharide fructose in which all six carbons are...
• Uniformly-labeled [13C]glucoseA non-radioactive, naturally occurring carbon 13 (13C) glucose isotopomer in which all six carbons are 13C...
• uniformly-labeled [13C]glutamineA uniformly-labeled radioconjugate composed of glutamine, a naturally occurring non-essential amino acid, in...
• uniformly-labeled [13C]lactateA uniformly-labeled radioconjugate composed of lactate in which all three carbons are labeled with the...
• unilateralHaving to do with one side of the body.
• unilateral salpingo-oophorectomySurgery to remove the ovary and fallopian tube on one side of the body.
• uninformative resultA negative test result in an individual where a clearly deleterious mutation has not been found in any family...
• United States Preventive Services Task ForceA volunteer group of health experts who review published research and make recommendations about prevention...
• UnituxinA drug used with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (IL-2), and...
• universal anti-CD7 CAR T cells RD13-01A preparation of universal T lymphocytes that have been genetically engineered to express a chimeric antigen...
• universal donor expanded TGF-beta-imprinted NK cellsA preparation of ex vivo expanded, universal donor, transforming growth factor-beta (TGF-beta; TGF-b)...
• UnloxcytA drug used to treat adults with cutaneous squamous cell carcinoma (a type of skin cancer) that has spread...
• unresectableUnable to be removed with surgery.
• unresectable gallbladder cancerCancer that has spread to the tissues around the gallbladder (such as the liver, stomach, pancreas...
• unresectedDescribes an organ, tissue, or cancer that has not been either partly or completely removed by surgery.
• unsealed internal radiation therapyRadiation therapy given by injecting a radioactive substance into the bloodstream or a body cavity, or by...
• uPAAn enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory...
• upacicalcetAn agonist of calcium-sensing receptors (CaSR), with potential use in the treatment of secondary...
• upacicalcet sodium hydrateThe sodium hydrate form of upacicalcet, an agonist of calcium-sensing receptors (CaSR), with potential use in...
• upinitatugA proprietary humanized monoclonal antibody against human sodium-dependent phosphate transport protein 2B...
• upinitatug rilsodotinA proprietary antibody-drug conjugate (ADC) composed of upinitatug , a proprietary, humanized monoclonal...
• u-plasminogen activatorAn enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory...
• upper endoscopyA procedure in which an endoscope is passed through the mouth and down the throat into esophagus, stomach...
• upper extremityThe part of the body that includes the arm, wrist, and hand.
• upper gastrointestinal endoscopyA procedure in which an endoscope is passed through the mouth and down the throat into esophagus, stomach...
• upper gastrointestinal seriesA series of x-ray pictures of the upper gastrointestinal (GI) tract, including the throat, esophagus...
• upper GI endoscopyA procedure in which an endoscope is passed through the mouth and down the throat into esophagus, stomach...
• upper GI seriesA series of x-ray pictures of the upper gastrointestinal (GI) tract, including the throat, esophagus...
• upper jawThe bones that form the upper part of the jaw, the roof of the mouth, and parts of the eye socket and nose...
• upregulationIn biology, the process by which a cell increases its response to a substance or signal from outside the cell...
• uproleselanA synthetic, glycomimetic molecule and E-selectin (CD62E) antagonist, with potential anti-thrombotic...
• upstagingIn cancer, changing the stage used to describe a patient’s cancer from a lower stage (less extensive) to a...
• urachusA fibrous cord that connects the urinary bladder to the umbilicus (navel). The urachus is formed as the...
• uracilA chemical compound that is used to make one of the building blocks of RNA. It is a type of pyrimidine.
• uracil ointmentA 0.1% topical formulation of uracil used to potentially lower the incidence of hand-foot syndrome (HFS) (or...
• ureaA substance formed by the breakdown of protein in the liver. The kidneys filter urea out of the blood and...
• urea nitrogenNitrogen in the blood that comes from urea (a substance formed by the breakdown of protein in the liver). The...
• urea/lactic acid-based creamA substance being studied in the treatment of hand-foot syndrome (a condition caused by chemotherapy and...
• urelumabA humanized agonistic monoclonal antibody targeting the CD137 receptor with potential immunostimulatory and...
• ureterThe tube that carries urine from the kidney to the bladder.
• ureteronephrectomySurgery to remove a kidney and its ureter. Also called nephroureterectomy.
• ureteroscopyA procedure that uses a ureteroscope to look inside the ureter (tube that connects the bladder to the kidney)...
• urethraThe tube through which urine leaves the body. It empties urine from the bladder.
• urethral cancerA rare cancer that forms in tissues of the urethra (the tube through which urine empties the bladder and...
• uric acidA waste product left over from normal chemical processes in the body and found in the urine and blood...
• uridineA nucleoside consisting of uracil and D-ribose and a component of RNA. Uridine has been studied as a rescue...
• uridine phosphorylase inhibitor TK-112690A 2,2'-anhydropyrimidine derivative and human uridine phosphorylase (UPase) inhibitor that can be used to...
• uridine triacetateA drug used in the emergency treatment of adults and children who receive too much fluorouracil or...
• urinalysisA test that determines the content of the urine.
• urinaryHaving to do with urine or the organs of the body that produce and get rid of urine.
• urinary diversionA surgical procedure to make a new way for urine to leave the body. It may involve redirecting urine into the...
• urinary incontinenceInability to hold urine in the bladder.
• urinary retentionA condition in which urine cannot empty from the bladder. Urinary retention can be acute and develop very...
• urinary systemThe organs that make urine and remove it from the body. The urinary system is divided into two parts. The...
• urinary tractThe organs that make urine and remove it from the body. The urinary tract is divided into two parts. The...
• urinary tract infectionA condition in which bacteria invade and grow in the urinary tract (the kidneys, ureters, bladder, and...
• urineFluid containing water and waste products. Urine is made by the kidneys, stored in the bladder, and leaves...
• urine cultureA laboratory test to check for bacteria, yeast, or other microorganisms in the urine. Urine cultures can help...
• urine cytologyTests performed on cells in urine to detect disease.
• URLC10 peptide/Montanide ISA51 vaccineA cancer vaccine containing URLC10 (up-regulated lung cancer 10) epitopes with potential immunostimulatory...
• URLC10-CDCA1-KOC1 multipeptide vaccineA cancer vaccine containing multiple peptide epitopes with potential immunostimulatory and antitumor...
• URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccineA cancer vaccine containing five peptide epitopes with potential immunostimulatory and antitumor activity...
• urokinaseAn enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory...
• urokinase plasminogen activator (uPA)-derived peptide A6A substance being studied in the treatment of cancer. Urokinase plasminogen activator (uPA)-derived peptide...
• urokinase-derived peptide A6An octapeptide (amino acids 136-143) derived from the proteolytic enzyme urokinase plasminogen activator...
• urokinase-plasminogen activatorAn enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory...
• urolithin A supplementA dietary supplement composed of urolithin A (Uro-A) that may be used to modulate mitochondrial activity, and...
• urologic oncologistA doctor who has special training in diagnosing and treating cancers of the male and female urinary tract and...
• urologistA doctor who has special training in diagnosing and treating diseases of the urinary organs in females and...
• urostomyAn operation to create an opening from inside the body to the outside, making a new way to pass urine.
• urothelial cancerCancer that begins in cells called urothelial cells that line the urethra, bladder, ureters, renal pelvis...
• urotheliumThe lining of the urinary tract, including the renal pelvis, ureters, bladder, and urethra.
• ursodiolA drug that is used to dissolve gallstones in people who can’t have surgery to remove them. It is also being...
• ursolic acidA pentacyclic triterpenoid found in various fruits, vegetables and medicinal herbs, with a variety of...
• Urtica dioica extractAn extract of Urtica dioica (stinging nettle; common nettle), a herbaceous perennial flowering plant in the...
• urticariaItchy, raised red areas on the skin. Urticaria are caused by a reaction to certain foods, drugs, infections...
• USB1 geneA gene that makes an enzyme involved in protecting a certain type of RNA from damage, which helps the RNA...
• USP1 inhibitor HSK39775An orally bioavailable small molecule inhibitor of the human deubiquitinating enzyme ubiquitin specific...
• USP1 Inhibitor ISM3091An orally bioavailable small molecule inhibitor of the human deubiquitinating enzyme ubiquitin specific...
• USP1 inhibitor KSQ-4279An orally bioavailable selective inhibitor of the ubiquitin specific protease 1 (USP1), with...
• USP1 inhibitor SIM0501An orally bioavailable non-covalent small molecule inhibitor of the human deubiquitinating enzyme ubiquitin...
• USP1 inhibitor TNG348An orally bioavailable small molecule inhibitor of the human deubiquitinating enzyme ubiquitin specific...
• USP14/UCHL5 inhibitor VLX1570An inhibitor of the 19S proteasome-specific deubiquitylating enzymes (DUBs) USP14 and UCHL5, with...
• USPSTFA volunteer group of health experts who review published research and make recommendations about prevention...
• ustekinumabAn orally available, human, IgG1kappa, monoclonal antibody directed against the p40 protein subunit of both...
• usual careThe care that a provider would normally give to their patients.
• utatrectinibA tropomyosin receptor kinase (TRK) inhibitor with potential antineoplastic activity. Upon administration...
• uterine cancerCancer that forms in tissues of the uterus (the small, hollow, pear-shaped organ in a woman's pelvis in which...
• uterine sarcomaA rare type of uterine cancer that forms in muscle or other tissues of the uterus (the small, hollow...
• uterusThe hollow, pear-shaped organ in a woman's pelvis. The uterus is where a fetus (unborn baby) develops and...
• UTIA condition in which bacteria invade and grow in the urinary tract (the kidneys, ureters, bladder, and...
• utideloneA genetically engineered epothilone analog with potential antineoplastic activity. Upon administration...
• UV radiationInvisible rays that are part of the energy that comes from the sun. UV radiation that reaches the Earth's...
• UV1 telomerase peptide vaccineA synthetic, peptide cancer vaccine directed against the human telomerase reverse transcriptase catalytic...
• UVA radiationInvisible rays that are part of the energy that comes from the sun. UVA radiation also comes from sun lamps...
• UVB radiationInvisible rays that are part of the energy that comes from the sun. UVB radiation causes sunburn, darkening...
• UVC radiationInvisible rays that are part of the energy that comes from the sun. Most UVC radiation from the sun is...
• uveaThe middle layer of the wall of the eye. The uvea has 3 main parts: (1) the choroid (the tissue layer filled...
• uveal melanomaA rare cancer that begins in the cells that make the dark-colored pigment, called melanin, in the uvea or...
• uveal tractThe middle layer of the wall of the eye. The uveal tract has 3 main parts: (1) the choroid (the tissue layer...
• uveitisA rare condition in which all or part of the uvea (middle layer of the wall of the eye) becomes inflamed. The...
• uvulaThe soft flap of tissue that hangs down at the back of the mouth (at the edge of the soft palate). Also...
• uzansertibAn orally available, small molecule and selective ATP-competitive pan-inhibitor of proviral integration sites...

164 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.