URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine

{
  "id": "MLC-T-ONC-017421",
  "term": "URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine containing five peptide epitopes with potential immunostimulatory and antitumor activity. Peptide epitopes in this vaccine are derived from: URLC10 (up-regulated lung cancer 10), TTK (TTK protein kinase), KOC1 (IGF II mRNA Binding Protein 3) and VEGFRs (vascular endothelial growth factor receptors) 1 and 2. Upon administration, URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, TTK, KCO1, VEGFR 1 and 2 peptides, resulting in cell lysis and decreased tumor growth.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/urlc10-ttk-koc1-vegfr1-vegfr2-multipeptide-vaccine/"
}