umbilical cord blood-derived CD4+/CD25+ T-regulatory cells CK0801

{
  "id": "MLC-T-ONC-017397",
  "term": "umbilical cord blood-derived CD4+/CD25+ T-regulatory cells CK0801",
  "field": "Oncology and biomedicine",
  "definition": "A preparation composed of allogeneic umbilical cord blood (UCB)-derived, ex vivo expanded and enhanced CD4+/CD25+ T-regulatory cells (Tregs) with potential immunomodulatory activity. Upon administration, the UCB-derived CD4+/CD25+ Tregs CK0801 may promote immunologic homeostasis and prevent autoimmunity by suppressing self-reactive T cells. This may induce tolerance to allogeneic organ transplants, prevent graft-versus-host disease (GvHD), and suppress autoimmune pathology.",
  "synonyms": [
    "UCB-derived CD4+CD25+ Tregs CK0801"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/umbilical-cord-blood-derived-cd4-plus-cd25-plus-t-regulatory-cells-ck0801/"
}