MLchartDataset catalogue

cord blood-derived expanded allogeneic natural killer cells

Term · Oncology and biomedicine · MLC-T-ONC-012773

A preparation of human umbilical cord blood (UCB)-derived and ex vivo-expanded allogeneic natural killer (NK) cells, with immunomodulating and cytotoxic activities. Upon infusion of the cord blood-derived expanded allogeneic NK cells, these cells recognize and bind to tumor cells, and secrete perforins, granzymes, and cytokines, which cause cancer cell lysis.

Table 1. Record
IdentifierMLC-T-ONC-012773
FieldOncology and biomedicine
SynonymsCB-derived expanded allogeneic NK cells; allogeneic CB-derived ex vivo-expanded NK cells; umbilical cord blood-derived expanded allogeneic natural killer cells; UCB-derived expanded allogeneic NK cells
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-012773",
  "term": "cord blood-derived expanded allogeneic natural killer cells",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of human umbilical cord blood (UCB)-derived and ex vivo-expanded allogeneic natural killer (NK) cells, with immunomodulating and cytotoxic activities. Upon infusion of the cord blood-derived expanded allogeneic NK cells, these cells recognize and bind to tumor cells, and secrete perforins, granzymes, and cytokines, which cause cancer cell lysis.",
  "synonyms": [
    "CB-derived expanded allogeneic NK cells",
    "allogeneic CB-derived ex vivo-expanded NK cells",
    "umbilical cord blood-derived expanded allogeneic natural killer cells",
    "UCB-derived expanded allogeneic NK cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cord-blood-derived-expanded-allogeneic-natural-killer-cells/"
}

Record 5,326 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.