cord blood-derived CMV/AdV/EBV/BKV-specific cytotoxic T lymphocytes

{
  "id": "MLC-T-ONC-012772",
  "term": "cord blood-derived CMV/AdV/EBV/BKV-specific cytotoxic T lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A population of allogeneic expanded cord blood (CB)-derived cytotoxic T lymphocytes (CTLs) that are specifically reactive to cytomegalovirus (CMV), Epstein-Barr virus (EBV), adenovirus (AdV), and human polyomavirus type I (BKV), with potential antiviral activity. Infusion of the CB-derived CMV/AdV /EBV/BKV-specific CTLs into CB hematopoietic stem cell transplant (HSCT) recipients may provide virus-specific cellular immunity, thereby preventing the infection or reactivation of certain viral-associated diseases.",
  "synonyms": [
    "cord blood-derived CMV/AdV/EBV/BKV-specific T cells",
    "allogeneic cord blood-derived CMV/AdV/EBV/BKV-specific CTLs",
    "UCB-derived CMV/AdV/EBV/BKV-specific T cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cord-blood-derived-cmv-adv-ebv-bkv-specific-cytotoxic-t-lymphocytes/"
}