MLchartDataset catalogue

Allogeneic virus-specific T lymphocytes R-MVST

Term · Oncology and biomedicine · MLC-T-ONC-009957

A preparation of allogeneic T lymphocytes generated from partially human leukocyte antigen (HLA)-matched healthy donors or from the original allogeneic hematopoietic stem cell transplantation (HSCT) donor, ex-vivo expanded, and specifically reactive to viruses that may include adenovirus (AdV), cytomegalovirus (CMV), Epstein-Barr virus (EBV) and human polyomavirus type I (BKV), with potential antiviral activity. Upon administration, the allogeneic virus-specific T lymphocytes R-MVST may kill AdV, CMV, EBV and/or BKV-infected cells, and may prevent or reduce the severity of viral infections by these pathogens.

Table 1. Record
IdentifierMLC-T-ONC-009957
FieldOncology and biomedicine
AbbreviationR-MVST
SynonymsR-MVST cells; rapidly-generated virus-specific T cells
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-009957",
  "term": "Allogeneic virus-specific T lymphocytes R-MVST",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of allogeneic T lymphocytes generated from partially human leukocyte antigen (HLA)-matched healthy donors or from the original allogeneic hematopoietic stem cell transplantation (HSCT) donor, ex-vivo expanded, and specifically reactive to viruses that may include adenovirus (AdV), cytomegalovirus (CMV), Epstein-Barr virus (EBV) and human polyomavirus type I (BKV), with potential antiviral activity. Upon administration, the allogeneic virus-specific T lymphocytes R-MVST may kill AdV, CMV, EBV and/or BKV-infected cells, and may prevent or reduce the severity of viral infections by these pathogens.",
  "abbreviation": "R-MVST",
  "synonyms": [
    "R-MVST cells",
    "rapidly-generated virus-specific T cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-virus-specific-t-lymphocytes-r-mvst/"
}

Record 844 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.