Allogeneic virus-specific T lymphocytes R-MVST
Term · Oncology and biomedicine · MLC-T-ONC-009957
A preparation of allogeneic T lymphocytes generated from partially human leukocyte antigen (HLA)-matched healthy donors or from the original allogeneic hematopoietic stem cell transplantation (HSCT) donor, ex-vivo expanded, and specifically reactive to viruses that may include adenovirus (AdV), cytomegalovirus (CMV), Epstein-Barr virus (EBV) and human polyomavirus type I (BKV), with potential antiviral activity. Upon administration, the allogeneic virus-specific T lymphocytes R-MVST may kill AdV, CMV, EBV and/or BKV-infected cells, and may prevent or reduce the severity of viral infections by these pathogens.
| Identifier | MLC-T-ONC-009957 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | R-MVST |
| Synonyms | R-MVST cells; rapidly-generated virus-specific T cells |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-009957",
"term": "Allogeneic virus-specific T lymphocytes R-MVST",
"field": "Oncology and biomedicine",
"definition": "A preparation of allogeneic T lymphocytes generated from partially human leukocyte antigen (HLA)-matched healthy donors or from the original allogeneic hematopoietic stem cell transplantation (HSCT) donor, ex-vivo expanded, and specifically reactive to viruses that may include adenovirus (AdV), cytomegalovirus (CMV), Epstein-Barr virus (EBV) and human polyomavirus type I (BKV), with potential antiviral activity. Upon administration, the allogeneic virus-specific T lymphocytes R-MVST may kill AdV, CMV, EBV and/or BKV-infected cells, and may prevent or reduce the severity of viral infections by these pathogens.",
"abbreviation": "R-MVST",
"synonyms": [
"R-MVST cells",
"rapidly-generated virus-specific T cells"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/allogeneic-virus-specific-t-lymphocytes-r-mvst/"
}
Record 844 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.