Allogeneic BK-specific cytotoxic T lymphocytes

{
  "id": "MLC-T-ONC-009836",
  "term": "Allogeneic BK-specific cytotoxic T lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "Allogeneic cytotoxic T lymphocytes (CTLs) that are specifically reactive to BK virus (BKV), with potential antiviral activity. Upon infusion of allogeneic BK-specific CTLs into immunocompromised patients who were infected with BKV after allogeneic stem cell transplantation, these cells exert a specific CTL response against BKV, thereby killing and eliminating the BKV-infected cells. BKV is a member of the polyomavirus family that may cause mild symptoms in normal, healthy people; however, BKV infection can lead to severe disease in immunocompromised patients.",
  "synonyms": [
    "allogeneic BK-CTLs",
    "allogeneic BK-specific CTLs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-bk-specific-cytotoxic-t-lymphocytes/"
}