MLchartDataset catalogue

allogeneic B7.1/HLA-A1 transfected tumor cell vaccine

Term · Oncology and biomedicine · MLC-T-ONC-009835

An allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human B7.1 (CD80 antigen) and human leukocyte antigen (HLA) A1, with potential antitumor activity. Vaccination with allogeneic B7.1/HLA-A1 transfected tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor cell proliferation.

Table 1. Record
IdentifierMLC-T-ONC-009835
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-009835",
  "term": "allogeneic B7.1/HLA-A1 transfected tumor cell vaccine",
  "field": "Oncology and biomedicine",
  "definition": "An allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human B7.1 (CD80 antigen) and human leukocyte antigen (HLA) A1, with potential antitumor activity. Vaccination with allogeneic B7.1/HLA-A1 transfected tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor cell proliferation.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-b7-1-hla-a1-transfected-tumor-cell-vaccine/"
}

Record 720 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.