allogeneic GM-CSF-secreting breast cancer vaccine
Term · Oncology and biomedicine · MLC-T-ONC-009892
An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens.
| Identifier | MLC-T-ONC-009892 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | GM-CSF BREAST VAC |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-009892",
"term": "allogeneic GM-CSF-secreting breast cancer vaccine",
"field": "Oncology and biomedicine",
"definition": "An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens.",
"abbreviation": "GM-CSF BREAST VAC",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/allogeneic-gm-csf-secreting-breast-cancer-vaccine/"
}
Record 778 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.