MAGE-3.A1 peptide vaccine

{
  "id": "MLC-T-ONC-014964",
  "term": "MAGE-3.A1 peptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic peptide cancer vaccine consisting of human leukocyte antigen HLA-A1-restricted peptide derived from human melanoma antigen 3 (MAGE-3) with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-3.A1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-3, resulting in tumor cell lysis. MAGE-3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types.",
  "synonyms": [
    "MAGE-3.A1",
    "HLA-A1-restricted MAGE-3 peptide vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mage-3-a1-peptide-vaccine/"
}