MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccine

{
  "id": "MLC-T-ONC-014965",
  "term": "MAGE-A1, Her-2/neu, FBP peptides ovarian cancer vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine containing multiple synthetic antigen peptides derived from MAGE-A1, Her-2/neu, and folate binding protein (FBP) with potential immunostimulating and antineoplastic properties. MAGE-A1, Her-2/neu, FBP peptides cancer vaccine includes the antigen peptides MAGE-A1:161-169, FBP:191-199, Her-2/neu:369-377, MAGE-A1:96-104, and Her-2/neu:754-762. Upon administration, this cancer vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing these antigen peptides, resulting in tumor cell lysis. MAGE-A1, Her-2/neu, and FBP proteins may be over-expressed in various cancer cell types, such as epithelial ovarian cancer cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/mage-a1-her-2-neu-fbp-peptides-ovarian-cancer-vaccine/"
}