TAEK-VAC-HerBy vaccine

{
  "id": "MLC-T-ONC-016959",
  "term": "TAEK-VAC-HerBy vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine targeting the tumor-associated antigen (TAA) HER-2/neu (ErbB-2), with potential immunomodulating and antineoplastic activities. Upon administration, TAEK-VAC-HerBy vaccine may induce a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells expressing the HER-2/neu antigen, which may result in the inhibition of proliferation in Her-2/neu-expressing tumor cells. Her-2/neu, a member of the epidermal growth factor receptor (EGFR) family of tyrosine kinases, is overexpressed in various tumor cell types.",
  "synonyms": [
    "TAEK-VAC-HerBy"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/taek-vac-herby-vaccine/"
}