folate binding protein J65 peptide vaccine

{
  "id": "MLC-T-ONC-013740",
  "term": "folate binding protein J65 peptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine comprised of human leukocyte antigen (HLA)-A2-restricted folate binding protein (FBP) epitope J65 (9 amino acids; EIWTFSTKV), with potential immunostimulatory and antineoplastic activities. Upon intradermal injection, FBP J65 peptide vaccine may induce a specific cytotoxic T-lymphocyte (CTL) response against J65 FBP-expressing tumor cell types. FBP is a membrane-bound, tumor-associated antigen overexpressed in various tumor types, including breast, ovarian and endometrial cancers. J65 is a strongly immunogenic peptide.",
  "synonyms": [
    "FBP J65 peptide vaccine",
    "J65 peptide vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/folate-binding-protein-j65-peptide-vaccine/"
}