multi-epitope anti-folate receptor peptide vaccine TPIV 200

{
  "id": "MLC-T-ONC-015341",
  "term": "multi-epitope anti-folate receptor peptide vaccine TPIV 200",
  "field": "Oncology and biomedicine",
  "definition": "A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor 1 (FOLR1; FR-alpha), with potential immunomodulating and antineoplastic activities. Upon intradermal administration, multi-epitope anti-folate receptor peptide vaccine TPIV 200 may induce a cytotoxic T-lymphocyte (CTL) response against FR-alpha-overexpressing tumor cells. FR-alpha is a high-affinity folate-binding protein and a member of the folate receptor family; this receptor is overexpressed in various cancer cell types.",
  "synonyms": [
    "TPIV 200 vaccine",
    "TPIV200/huFR-1"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/multi-epitope-anti-folate-receptor-peptide-vaccine-tpiv-200/"
}