multi-epitope HER2 peptide vaccine H2NVAC

{
  "id": "MLC-T-ONC-015343",
  "term": "multi-epitope HER2 peptide vaccine H2NVAC",
  "field": "Oncology and biomedicine",
  "definition": "A peptide vaccine containing four immunogenic epitopes derived from the tumor-associated antigen (TAA) human epidermal growth factor receptor 2 (HER2; HER-2; ErbB2; Neu), with potential immunomodulating and antineoplastic activities. Upon intradermal administration, multi-epitope HER2 peptide vaccine H2NVAC may induce a helper T-cell mediated immune response against HER2-overexpressing tumor cells. This may result in long-term immunopotentiation against HER2-expressing tumor cells by increasing the helper T-cell response. HER2, a tyrosine kinase receptor for epidermal growth factor (EGF), is overexpressed in various cancer cell types.",
  "synonyms": [
    "HER2 peptide vaccine H2NVAC",
    "HER2 specific helper T-cell epitope vaccine H2NVAC"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/multi-epitope-her2-peptide-vaccine-h2nvac/"
}