allogeneic cytomegalovirus-specific cytotoxic T lymphocytes

{
  "id": "MLC-T-ONC-009875",
  "term": "allogeneic cytomegalovirus-specific cytotoxic T lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to the herpes virus cytomegalovirus (CMV) with potential immunomodulating and antiviral activities. Upon immunoprophylactic adoptive cell therapy infusion with allogeneic cytomegalovirus-specific cytotoxic T lymphocytes, these CTLs may help reconstitute CMV-specific CTL responses in CMV-infected immunocompromised hosts after allogeneic hematopoietic stem cell transplant, thereby potentially preventing the occurrence of CMV viral disease or reducing the amount of antiviral drug therapy.",
  "abbreviation": "allogeneic CMV-specific CTLs",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-cytomegalovirus-specific-cytotoxic-t-lymphocytes/"
}