cytomegalovirus IE-1-specific cytotoxic T lymphocytes

{
  "id": "MLC-T-ONC-012885",
  "term": "cytomegalovirus IE-1-specific cytotoxic T lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "Cytotoxic T-lymphocytes (CTLs), specifically reactive to the cytomegalovirus (CMV) immediate early-1 (IE-1) protein, with immunomodulating activity. Adoptive immunotherapy with cytomegalovirus IE-1-specific cytotoxic T lymphocytes may help reconstitute CD8+ cytomegalovirus-specific CTL responses in CMV-infected immunocompromised hosts. IE-1 is one of the first CMV antigens expressed by CMV-infected cells, predominantly inducing a CD8+ CTL response.",
  "abbreviation": "CMV IE-1-specific CTL",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cytomegalovirus-ie-1-specific-cytotoxic-t-lymphocytes/"
}