allogeneic AdV/CMV/EBV-specific T lymphocytes

{
  "id": "MLC-T-ONC-009791",
  "term": "allogeneic AdV/CMV/EBV-specific T lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of human leukocyte antigen (HLA)-matched or HLA-mismatched, allogeneic CD4+ and CD8+ T lymphocytes, ex vivo incubated with synthetic peptides of the viral antigens of the three human viruses adenovirus (AdV), cytomegalovirus (CMV) and Epstein-Barr virus (EBV), with potential antiviral activity. Upon administration of the allogeneic AdV/CMV/EBV-specific T lymphocytes after allogeneic hematopoietic stem cell transplantation (HSCT), these T lymphocytes may kill AdV, CMV, and/or EBV-infected cells, and may prevent or reduce the severity of viral infections by these pathogens.",
  "synonyms": [
    "allogeneic AdV/CMV/EBV multi-virus-specific T lymphocytes"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-adv-cmv-ebv-specific-t-lymphocytes/"
}