cord blood-derived CAR T cells

{
  "id": "MLC-T-ONC-012771",
  "term": "cord blood-derived CAR T cells",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of umbilical cord blood (CB)-derived T lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) that targets an as of yet unidentified tumor-associated antigen (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration of the cord blood derived CAR T cells, the T cells target, bind to and induce selective cytotoxicity in tumor cells expressing the TAA.",
  "synonyms": [
    "CB-derived CAR T cells",
    "cord blood CAR T cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cord-blood-derived-car-t-cells/"
}