MLchartDataset catalogue

UV1 telomerase peptide vaccine

Term · Oncology and biomedicine · MLC-T-ONC-017435

A synthetic, peptide cancer vaccine directed against the human telomerase reverse transcriptase catalytic subunit (hTERT) with potential immunomodulating activity. Vaccination with the UV1 telomerase peptide may stimulate cytotoxic T-cells to recognize and kill telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation.

Table 1. Record
IdentifierMLC-T-ONC-017435
FieldOncology and biomedicine
SynonymsUV1/hTERT peptide vaccine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-017435",
  "term": "UV1 telomerase peptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic, peptide cancer vaccine directed against the human telomerase reverse transcriptase catalytic subunit (hTERT) with potential immunomodulating activity. Vaccination with the UV1 telomerase peptide may stimulate cytotoxic T-cells to recognize and kill telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation.",
  "synonyms": [
    "UV1/hTERT peptide vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/uv1-telomerase-peptide-vaccine/"
}

Record 17,036 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.