hTERT I540/R572Y/D988Y multipeptide vaccine

{
  "id": "MLC-T-ONC-014221",
  "term": "hTERT I540/R572Y/D988Y multipeptide vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A peptide vaccine consisting of multiple epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with potential immunostimulating and antineoplastic activities. hTERT I540/R572Y/D988Y multipeptide vaccine contains strongly antigenic peptide epitopes I540 (9-mer), R572Y (9-mer) and D988Y (10-mer). Vaccination with this agent may elicit a cytotoxic T cell (CTL) response against telomerase-expressing tumor cells. Directly linked to tumorigenesis, telomerase is expressed in the majority of human cancer cells but is infrequently expressed in normal cells.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/htert-i540-r572y-d988y-multipeptide-vaccine/"
}