Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: H (632)

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H and E stainingA common laboratory method that uses two dyes called hematoxylin and eosin that make it easier to see...
H. pyloriA type of bacterium that causes inflammation and ulcers in the stomach or small intestine. People with H...
H1299 tumor cell lysate vaccineA cell lysate derived from a lung cancer cell line, H1299, with potential immunostimulatory and...
H3.3K27M-specific peptide vaccineA vaccine composed of a peptide derived from histone H3.3 containing the amino acid substitution mutation...
H3K27M long peptide vaccineA vaccine composed of a twenty seven (27) amino acid long peptide derived from histone H3 containing the...
hA20A substance being studied in the treatment of several types of lymphoma. It binds to the protein CD20, which...
HAAH lambda phage vaccine SNS-301A nanoparticle-based cancer vaccine composed of a neutralized bacteriophage Lambda construct that is...
HAARTTreatment that uses a combination of three or more drugs to treat HIV infection. HAART stops the virus from...
Haemophilus influenzae b vaccineA vaccine against serotype b of the Gram-negative bacterium H. influenzae (Hib). Hib vaccines contain...
hafnium oxide-containing nanoparticles NBTXR3A suspension of nanoparticles containing inert inorganic hafnium oxide (HfO2) crystals with potential...
hair follicleA shaft or opening on the surface of the skin through which hair grows.
hairy cell leukemiaA rare type of leukemia in which abnormal B-lymphocytes (a type of white blood cell) are present in the bone...
HalavenA drug used to treat certain types of breast cancer and liposarcoma (a type of soft tissue sarcoma) that have...
HaldolA drug used to treat certain mental and neurological disorders. It is also being studied in the treatment of...
half-siblingA person’s brother or sister who has one parent in common.
halichondrin analogue E7130A halichondrin analogue derived from a marine sponge with potential antineoplastic activity. Upon intravenous...
hallucinationA sight, sound, smell, taste, or touch that a person believes to be real but is not real. Hallucinations can...
halofuginone hydrobromideA substance that is being studied for its ability to slow the growth of connective tissue and to prevent the...
haloperidolA drug used to treat certain mental and neurological disorders. It is also being studied in the treatment of...
Halsted radical mastectomySurgery to remove the whole breast, all of the lymph nodes under the arm, and the chest wall muscles under...
hamartomaA benign (not cancer) growth made up of an abnormal mixture of cells and tissues normally found in the area...
hand-foot syndromeA condition marked by pain, swelling, numbness, tingling, or redness of the hands or feet. It sometimes...
haploidentical donorA term used to describe a tissue donor whose HLA tissue type partially matches (usually 50%) the HLA tissue...
haploidentical natural killer cells K-NK002A population of ex-vivo expanded and activated haploidentical donor-derived natural killer (NK) cells, with...
haploinsufficiencyThe situation that occurs when one copy of a gene is inactivated or deleted and the remaining functional copy...
haplotypeA set of closely linked genetic markers or DNA variations on a chromosome that tend to be inherited together.
happy majorA plant whose seeds and root have been used in some cultures to treat certain medical problems. It may have...
hard palateThe front, bony part of the roof of the mouth.
Hashimoto diseaseAn autoimmune condition of the thyroid gland (a gland located beneath the larynx). It is caused by the...
Hashimoto thyroiditisAn autoimmune condition of the thyroid gland (a gland located beneath the larynx). It is caused by the...
hawthorn fruitThe fruit of the hawthorn tree or bush. It has been used in some cultures to treat certain medical problems...
hazard ratioA measure of how often a particular event happens in one group compared to how often it happens in another...
HBOC syndromeAn inherited disorder in which the risk of breast cancer (especially before the age of 50) and ovarian cancer...
HBVA virus that causes hepatitis (inflammation of the liver). It is carried and passed to others through the...
HBV mRNA vaccineA vaccine consisting of a mRNA delivery vector encapsulating messenger RNA (mRNA) encoding an unspecified...
HCAA chemical that is formed when meat, poultry, or fish is cooked at high temperatures, such as frying...
HCCA type of cancer that forms in liver cells called hepatocytes. Hepatocytes are the most common cells of the...
HCD20A substance being studied in the treatment of several types of lymphoma. It binds to the protein CD20, which...
hCRFA substance being studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part...
HCTThe amount of whole blood that is made up of red blood cells. It depends on the number and size of red blood...
HCVA virus that causes hepatitis (inflammation of the liver). It is carried and passed to others through the...
HCV DNA vaccine INO-8000A multi-antigen DNA vaccine consisting of plasmids encoding the hepatitis C virus (HCV) nonstructural...
HDACAn enzyme that removes a small molecule called an acetyl group from histones (proteins found in chromosomes)...
HDAC class I/IIb inhibitor HG146An orally available inhibitor of histone deacetylase (HDAC) classes I and IIb with potential antineoplastic...
HDAC inhibitorA substance that causes a chemical change that stops tumor cells from dividing. HDAC inhibitors are being...
HDAC inhibitor CHR-2845A hydroxamic acid-derived histone deacetylase (HDAC) inhibitor with potential antineoplastic activity...
HDAC inhibitor CKD-581A highly water-soluble, pan histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity...
HDAC inhibitor OBP-801An inhibitor of histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon...
HDAC inhibitor REC-2282An orally available phenylbutyrate-derived histone deacetylase (HDAC) inhibitor, with potential...
HDAC inhibitor SHP-141A topical formulation containing the histone deacetylase (HDAC) inhibitor with potential antineoplastic...
HDAC inhibitor SNDX-275A substance being studied in the treatment of several types of cancer. It blocks enzymes needed for cell...
HDAC6 inhibitor KA2507An orally bioavailable inhibitor of histone deacetylase (HDAC) type 6 (HDAC6; HDAC-6), with potential...
HDAC8 inhibitor NBM-BMXAn orally bioavailable inhibitor of histone deacetylase (HDAC) type 8 (HDAC8; HDAC-8), with potential...
HDAC/EGFR/Her2 inhibitor CUDC-101A multi-targeted, small-molecule inhibitor of histone deacetylase (HDAC), epidermal growth factor receptor...
HDGCA rare, inherited disorder that increases the risk of developing a type of stomach cancer called diffuse...
HDM2 inhibitor MK-8242An orally bioavailable inhibitor of human homolog of double minute 2 (HDM2), with potential antineoplastic...
HDRAn amount of radiation that is greater than that given in typical radiation therapy. HDR is precisely...
HE4A protein found on cells that line the lungs and reproductive organs, such as the ovaries. HE4 may be found...
head and neck cancerCancer that forms in certain areas of the head and neck, including tissues in the nasal cavity (the hollow...
healing touchA form of complementary and alternative medicine based on the belief that vital energy flows through the...
health care providerA licensed person or organization that provides health care services. Examples of health care providers...
health care proxyA type of advance directive that gives a person (called a proxy) the authority to make medical decisions for...
health disparityA type of preventable health difference that is closely linked with social, political, economic, and...
health equityA situation in which all people are given the chance to live as healthy a life as possible regardless of...
health historyA record of information about a person’s health. A personal health history may include information about...
Health Insurance Portability and Accountability ActA 1996 U.S. law that allows workers and their families to keep their health insurance when they change or...
health insurance premiumThe amount of money that a patient pays monthly to a health insurance company for health care coverage...
healthy controlIn a clinical study, a person who does not have the disorder or disease being studied. Results from healthy...
heart cancerA rare cancer that develops in tissues of the heart. Also called cardiac sarcoma.
heart diseaseA type of disease that affects the heart or blood vessels. The risk of certain heart diseases may be...
heart rateIn medicine, the number of times the heart beats within a certain time period, usually a minute. The heart...
heat shock factor 1 pathway inhibitor NXP800An orally bioavailable fluorobisamide and heat shock factor 1 (HSF1) pathway inhibitor, with potential...
heat-killed bacterium Mycobacterium obuense IMM-101A suspension of heat-killed Mycobacterium (M.) obuense, a non-pathogenic and naturally-occurring bacterium...
heat-shock proteinOne of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of...
heat-treated varicella-zoster virus vaccine V212A heat-treated varicella-zoster virus (VZV) vaccine with potential immunomodulating activity. Upon...
Hec1/Nek2 inhibitor T-1101 tosylateThe tosylate salt form of T-1101, an orally bioavailable inhibitor of highly expressed in cancer 1 (Hec1) and...
hedgehog inhibitor NLM-001A Hedgehog (Hh) pathway inhibitor, with potential immunomodulating and antineoplastic activities. Upon...
hedgehog signaling pathwayDescribes a group of proteins that work together in a cell to send signals from the cell membrane to the...
Hedyotis diffusaAn herb used in traditional Chinese medicine to treat certain medical problems. It has been used to boost the...
helical computed tomographyA procedure that uses a computer linked to an x-ray machine to make a series of detailed pictures of areas...
helical tomotherapyA type of therapy in which radiation is aimed at a tumor from many different directions. The patient lays on...
Helicobacter pyloriA type of bacterium that causes inflammation and ulcers in the stomach or small intestine. People with...
Helicobacter pylori therapeutic vaccine IMX101A Helicobacter pylori (H. pylori) therapeutic vaccine comprised of three components: two antigens, the...
helper T cellA type of immune cell that stimulates killer T cells, macrophages, and B cells to make immune responses. A...
hemagglutinin-neuraminidaseA protein found in the outer coat of paramyxoviruses. This protein helps virus particles bind to cells...
HemangeolA drug that contains the active ingredient propranolol hydrochloride and is used to treat infants 5 weeks to...
hemangiopericytomaA type of cancer involving blood vessels and soft tissue.
hemangiosarcomaA type of cancer that begins in the cells that line blood vessels.
hematocritThe amount of whole blood that is made up of red blood cells. It depends on the number and size of red blood...
hematogenousOriginating in the blood or spread through the bloodstream.
hematologic cancerCancer that begins in blood-forming tissue, such as the bone marrow, or in the cells of the immune system...
hematologistA doctor who has special training in diagnosing and treating blood disorders.
hematomaA pool of mostly clotted blood that forms in an organ, tissue, or body space. A hematoma is usually caused by...
hematopathology laboratoryA laboratory that specializes in doing tests that help to diagnose and treat diseases of the blood, bone...
hematopoiesisThe formation of new blood cells.
hematopoietic growth factorA group of proteins that causes blood cells to grow and mature.
hematopoietic stem cellAn immature cell that can develop into all types of blood cells, including white blood cells, red blood...
hematopoietic tissueTissue in which new blood cells are formed.
hematoporphyrin derivativeA drug used in photodynamic therapy that is absorbed by tumor cells. When exposed to light, it becomes active...
hematoxylin and eosin stainingA common laboratory method that uses two dyes called hematoxylin and eosin that make it easier to see...
hematuriaBlood in the urine.
hemeThe part of certain molecules that contains iron. The heme part of hemoglobin is the substance inside red...
hemiasterlin analogue E7974An analogue of the sponge-derived anti-microtubule tripeptide hemiasterlin with antimitotic and potential...
hemihyperplasiaA condition in which one side of the body or a part of one side is larger than the other. Children with...
hemihypertrophyA condition in which one side of the body or a part of one side is larger than the other. Children with...
hemilaryngectomyAn operation to remove one side of the larynx (voicebox).
hemizygousA term that describes a person who has only one copy of a gene rather than the usual two copies. Hemizygosity...
hemochromatosisA condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the...
hemoglobinA protein inside red blood cells that carries oxygen from the lungs to tissues and organs in the body and...
hemolysisThe breakdown of red blood cells. Some diseases, medicines, and toxins may cause red blood cells to break...
hemophagocytic lymphohistiocytosisA rare disorder in which histiocytes and lymphocytes (types of white blood cells) build up in organs...
hemophiliaGroup of hereditary disorders in which affected individuals fail to make enough of certain proteins needed to...
hemoporfinA light-activated compound, with potential photosensitizing activity upon photodynamic therapy (PDT). Upon...
hemoptysisCoughing or spitting up blood from the respiratory tract.
hemorrhageIn medicine, loss of blood from damaged blood vessels. A hemorrhage may be internal or external, and usually...
hemorrhagic cerebrovascular accidentA type of stroke that occurs when a blood vessel in the brain or on the surface of the brain leaks or breaks...
hemorrhagic cystitisA condition in which the lining of the bladder becomes inflamed and starts to bleed. The blood can be seen in...
hemorrhagic strokeA type of stroke that occurs when a blood vessel in the brain or on the surface of the brain leaks or breaks...
hemorrhoidAn enlarged or swollen blood vessel, usually located near the anus or the rectum.
hempAn herb that comes from a variant of the Cannabis sativa plant and contains fiber, seeds, and oil used to...
henatinib maleateThe maleate salt form of henatinib, an orally bioavalable, multitargeted tyrosine kinase inhibitor with...
heparan sulfate glycosaminoglycan mimetic nanopolymer mouthwashA nanopolymer-based mouthwash formulation containing a mimetic of the glycosaminoglycan (GAG) heparan...
heparinA substance that slows the formation of blood clots. Heparin is made by the liver, lungs, and other tissues...
heparin calciumThe calcium salt form of heparin. As a glycosaminoglycan anticoagulant, heparin calcium binds to antithrombin...
heparin sodiumThe sodium salt form of heparin. As a glycosaminoglycan anticoagulant, heparin sodium binds to antithrombin...
hepatectomySurgery to remove all or part of the liver.
hepaticRefers to the liver.
hepatic arterial infusionA procedure to deliver chemotherapy directly to the liver. Catheters are put into an artery in the groin that...
hepatic arterial occlusionA block in blood flow to the liver. It can happen while giving chemotherapy through a catheter in the hepatic...
hepatic arteryThe major blood vessel that carries blood to the liver.
hepatic portal veinA blood vessel that carries blood to the liver from the intestines, spleen, pancreas, and gallbladder. Also...
hepatic veno-occlusive diseaseA condition in which some of the veins in the liver are blocked. This causes a decrease in blood flow inside...
hepatitisDisease of the liver causing inflammation. Symptoms include an enlarged liver, fever, nausea, vomiting...
hepatitis A vaccineA vaccine used to prevent infection with the hepatitis A virus, which causes a serious liver disease. The...
hepatitis A virusA virus that causes a serious liver disease. It is usually spread by contact with an infected person’s stool...
hepatitis B vaccine (recombinant)A non-infectious mixture containing recombinant hepatitis B surface antigen (HBsAg) in a liquid vehicle...
hepatitis B virusA virus that causes hepatitis (inflammation of the liver). It is carried and passed to others through the...
hepatitis B virus antigen peptides/hepatitis G2 cell protein lysate-activated dendritic cellsA cell-based cancer vaccine composed of autologous dendritic cells (DCs) ex vivo activated with the hepatitis...
hepatitis B virus antisense oligonucleotide AHB-137An unconjugated antisense oligonucleotide (ASO) targeting human hepatitis B virus (HBV), with potential...
hepatitis C immune globulin intravenousA human plasma-derived, polyclonal, intravenous immunoglobulin G (IgG) formulation containing high levels of...
hepatitis C virusA virus that causes hepatitis (inflammation of the liver). It is carried and passed to others through the...
hepatitis D virusA type of hepatitis virus that may be present in the body at the same time as the hepatitis B virus. It makes...
hepatitis delta virusA type of hepatitis virus that may be present in the body at the same time as the hepatitis B virus. It makes...
hepatitis E virusA virus that causes hepatitis (inflammation of the liver). It is usually spread through food that has been...
hepatitis G virusA virus that may be found in patients with hepatitis (inflammation of the liver). It is spread to others...
hepatobiliaryHaving to do with the liver, bile ducts, and/or gallbladder.
hepatoblastomaA type of liver tumor that occurs in infants and children.
hepatocellular carcinomaA type of cancer that forms in liver cells called hepatocytes. Hepatocytes are the most common cells of the...
hepatocyteA liver cell.
hepatolenticular degenerationA rare, inherited disorder in which too much copper builds up in the body. The extra copper is stored in the...
hepatomaA liver tumor.
hepatomegalyEnlarged liver.
hepsulfamA bisulfamic ester which is similar in structure to busulfan and belongs to the family of drugs known as...
HepzatoA drug that contains the active ingredient melphalan hydrochloride and is used to treat adults with uveal...
HER1A protein found on certain types of cells that binds to a substance called epidermal growth factor. The HER1...
HER1 geneA gene that makes a protein that is involved in cell growth and cell survival. Mutated (changed) forms of the...
HER2A protein involved in normal cell growth. HER2 may be made in larger than normal amounts by some types of...
HER2 ECD+TM virus-like replicon particles vaccine AVX901A cancer vaccine based on virus-like replicon particles (VRP) packaged with an alphaviral vector encoding the...
HER2 inhibitor DZD1516An orally bioavailable, blood brain barrier (BBB) penetrable inhibitor of the receptor tyrosine kinase human...
HER2 inhibitor ELVN-002An orally bioavailable, irreversible inhibitor of the receptor tyrosine kinase human epidermal growth factor...
HER2 inhibitor IAM1363An orally bioavailable, immediate release (IR) capsule formulation containing a selective and irreversible...
HER2 inhibitor SPH5030An orally bioavailable, irreversible inhibitor of the receptor tyrosine kinase human epidermal growth factor...
HER2 inhibitor TAS0728An orally available covalent inhibitor of human epidermal growth factor receptor 2 (HER2; ERBB2), with...
HER2 inhibitor ZN-A-1041An orally bioavailable inhibitor of the receptor tyrosine kinase human epidermal growth factor receptor 2...
HER2 mutant-selective inhibitor NVL-330An orally bioavailable mutant-selective inhibitor of the receptor tyrosine kinase human epidermal growth...
HER2 negativeDescribes cells that have a small amount or none of a protein called HER2 on their surface. In normal cells...
HER2 positiveDescribes cells that have a protein called HER2 on their surface. In normal cells, HER2 helps control cell...
HER2 testA laboratory test that measures the amount of HER2 protein on cancer cells or how many copies of the HER2...
HER2 tri-specific natural killer cell engager DF1001An engineered molecule based on tri-specific natural killer (NK) cell engager therapies (TriNKET) that is...
HER2Bi-armed activated T cellsActivated T cells (ATC) that have been coated with bispecific antibodies (BiAb), with potential...
HER2-low breast cancerA type of breast cancer in which the cancer cells have a small amount of a protein called HER2 on their...
HER2/neuA protein involved in normal cell growth. HER2/neu may be made in larger than normal amounts by some types of...
HER-2-neu, CEA peptides, GM-CSF, Montanide ISA-51 vaccineA vaccine comprised of HER-2-neu and carcinoembryonic antigen synthetic (CEA) peptides, combined with the...
HER-2/neu intracellular domain proteinThe cytoplasmic domain or intracellular domain (ICD) of the HER2/neu protein that exhibits tyrosine kinase...
HER-2/neu peptide vaccineA cancer vaccine comprised of peptides derived from the extracellular domain of the tumor-associated antigen...
HER2/neu peptide vaccine GLSI-100A cancer peptide vaccine comprised of the epitope GP2, a nine amino acid peptide (amino acids 654-662)...
HER2/neu testA laboratory test that measures the amount of HER2/neu protein on cancer cells or how many copies of the...
HER-2-positive B-cell peptide antigen IMU-131A cancer vaccine consisting of a fusion peptide, composed of three peptides derived from the extracellular...
HER2-pulsed type-1 polarized autologous dendritic cell vaccineA dendritic cell (DC)-based cancer vaccine composed of autologous, type-1 polarized dendritic cells (DCs)...
HER2-targeted DARPin MP0274A proprietary, designed ankyrin repeat proteins (DARPin)-based agent targeting the tyrosine kinase receptor...
HER2-targeted hypoxia-stimulated CAR T cellsA preparation of T lymphocytes that have been genetically modified to express a hypoxia-stimulated chimeric...
HER2-targeted liposomal doxorubicin hydrochloride HF158K1An antibody liposomal formulation containing the hydrochloride (HCl) salt form of the antineoplastic...
HER2-targeted liposomal doxorubicin hydrochloride MM-302An antibody-targeted lipidic nano-carrier containing the antineoplastic anthracycline antibiotic doxorubicin...
HER2-targeting antibody Fc fragment FS102A proprietary, antibody fragment composed of a constant (Fc) region that is engineered to bind to the...
herbA non-woody, seed-bearing plant, or its parts, used for its medicinal, savory, or aromatic qualities.
herba scutellaria barbataA Chinese herb isolated from the plant Scutellaria barbata D. Don (Lamiaceae) with potential antineoplastic...
herba Scutellaria barbataeAn herb used in traditional Chinese medicine to treat certain medical problems. It may have anticancer...
herbalHaving to do with plants.
herbal cigaretteA type of cigarette that contains a mixture of flowers, herbs, and other natural ingredients. Herbal...
herbal medicineA type of medicine that uses roots, stems, leaves, flowers, or seeds of plants to improve health, prevent...
herbal polysaccharide saliva substituteA plant-based, proprietary formulation of saliva substitute with potential anti-xerostomia activity...
herbal supplementA product made from a plant that is thought to be useful in treating disease or staying healthy. Herbal...
herbicideA chemical that kills plants.
HerceptinA drug used alone or with other drugs to treat certain types of breast cancer, stomach cancer, and...
Herceptin HylectaA combination of trastuzumab and hyaluronidase used alone or with other drugs to treat adults with certain...
HercessiA drug used alone or with other drugs to treat certain types of breast cancer, stomach cancer, and...
herd immunityProtection from an infectious disease as a result of living in a community where a large number of people are...
hereditaryIn medicine, describes the passing of genetic information from parent to child through the genes in sperm and...
hereditary breast and ovarian cancer syndromeAn inherited disorder in which the risk of breast cancer (especially before the age of 50) and ovarian cancer...
hereditary cancer syndromeA type of inherited disorder in which there is a higher-than-normal risk of certain types of cancer...
hereditary diffuse gastric cancerA rare, inherited disorder that increases the risk of developing a type of stomach cancer called diffuse...
hereditary hemochromatosisAn inherited condition in which too much iron builds up in the body. The extra iron is stored in the body’s...
hereditary leiomyomatosis and renal cell cancerA rare, inherited disorder in which benign (not cancer) skin lesions called leiomyomas form in the smooth...
hereditary nonpolyposis colorectal cancerAn inherited disorder that increases the risk of developing colorectal cancer, endometrial cancer, ovarian...
hereditary papillary renal cancerA rare, inherited disorder that increases the risk of a type of kidney cancer called type 1 papillary kidney...
hereditary papillary renal carcinomaA rare, inherited disorder that increases the risk of a type of kidney cancer called type 1 papillary kidney...
hereditary paraganglioma-pheochromocytoma syndromeA rare, genetic disorder marked by tumors called paragangliomas, which are found in paraganglia. Paraganglia...
hereditary predispositionAn inherited increase in the risk of developing a disease. Also called genetic predisposition, genetic...
hereditary syndromeA disorder caused by mutations (changes) in certain genes or chromosomes that are passed down from parent to...
heritabilityThe proportion of variation in a population trait that can be attributed to inherited genetic factors...
heritableIn medicine, describes a characteristic or trait that can be passed from a parent to a child through the...
heritageSomething handed down from the past, such as a tradition, birthright, or inherited traits.
herniaThe bulging of an internal organ through a weak area or tear in the muscle or other tissue that holds it in...
heroinA highly addictive substance once used to treat severe pain but is now illegal to use or sell in the United...
herpes simplex virusA type of virus that causes herpes infections and has DNA as its genetic material. There are two types of...
herpes zosterA common condition that occurs when the virus that causes chickenpox is reactivated in the body. After having...
herpesvirusA member of the herpes family of viruses.
HerzumaA drug used alone or with other drugs to treat certain types of breast cancer, stomach cancer, and...
hetastarchA synthetic, nonionic hydroxyethyl derivative of starch used as a plasma expander when prepared in an...
heterocyclic amineA chemical that is formed when meat, poultry, or fish is cooked at high temperatures, such as frying...
heterodimeric interleukin-15A fusion protein complex composed of heterodimeric IL-15 (hetIL-15), which consists of a synthetic form of...
heteroduplex analysisA laboratory method used to detect sequence differences between normal DNA and the DNA to be tested...
heterogeneity logarithm of the odds scoreA statistical estimate of whether two genetic loci are physically near enough to each other (or “linked”) on...
heterogeneousMade up of elements or ingredients that are not alike.
heterogeneously dense breast tissueA term used to describe breast tissue that has large areas of dense fibrous tissue and glandular tissue and...
heterogenicDerived from a different source or species. Also called heterogenous.
heterogenousDerived from a different source or species. Also called heterogenic.
heterozygous genotypeA term that describes having two different versions of the same gene (one inherited from the mother and one...
hetrombopag olamineThe orally active ethanolamine salt of hetrombopag, a small-molecule, nonpeptide thrombopoietin receptor...
hexamethylene bisacetamideA hybrid polar-planar compound with potential antineoplastic activity that induces terminal differentiation...
hexaminolevulinateThe hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties. As a precursor of photoactive...
hexaminolevulinate hydrochlorideThe hydrochloride salt form of hexaminolevulinate, a hexyl ester of the heme precursor 5-aminolevulinic acid...
hexyl 5-aminolevulinateA substance that is used to find and kill tumor cells. It enters tumor cells and becomes activated when...
HGS-ETR1A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL R1 on...
HGS-ETR2A substance being studied in the treatment of some types of cancer. It binds to a protein called TRAIL-R2 on...
HHSThe U.S. federal government agency responsible for protecting the public’s health and providing important...
HHVA type of virus that causes herpes infections and has DNA as its genetic material. There are two types of...
HHV8A type of virus that causes Kaposi sarcoma (a rare cancer in which lesions grow in the skin, lymph nodes...
HIFOne of a group of proteins that play an important role in how cells respond to changing levels of oxygen...
HIF-1alpha inhibitor PX-478An orally active small molecule with potential antineoplastic activity. Although its mechanism of action has...
HIF2a RNAi ARO-HIF2An RNA interference (RNAi) targeting hypoxia-inducible factor 2alpha (HIF-2a), with potential antineoplastic...
HIF-2alpha inhibitor AB521An orally bioavailable allosteric inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential...
HIF2alpha inhibitor DFF332An inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential antineoplastic activity. Upon...
HIF-2alpha inhibitor HS-10516An orally bioavailable inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential antineoplastic...
HIF2-alpha inhibitor NKT2152An orally available inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential antineoplastic...
HIF-2alpha inhibitor PT2385An orally active, small molecule inhibitor of hypoxia inducible factor (HIF)-2alpha, with potential...
HIFUA procedure in which high-energy sound waves are aimed directly at an area of abnormal cells or tissue in the...
high blood pressureA blood pressure of 140/90 or higher. High blood pressure usually has no symptoms. It can harm the arteries...
high blood sugarHigher than normal amount of glucose (a type of sugar) in the blood. High blood sugar can be a sign of...
high gradeA term used to describe cells and tissue that look abnormal under a microscope. High-grade cancer cells tend...
high-amylose resistant starchA resistant starch-based dietary fiber supplement derived from a variety of high-amylose corn rich in...
high-dose chemotherapyAn intensive drug treatment to kill cancer cells, but that also destroys the bone marrow and can cause other...
high-dose radiationAn amount of radiation that is greater than that given in typical radiation therapy. High-dose radiation is...
high-dose-rate remote brachytherapyA type of internal radiation treatment in which the radioactive source is removed between treatments. Also...
high-dose-rate remote radiation therapyA type of internal radiation treatment in which the radioactive source is removed between treatments. Also...
high-energy photon therapyA type of radiation therapy that uses high-energy photons (units of light energy). High-energy photons...
high-grade DCISA condition in which cells that look very different from normal cells under a microscope are found in the...
high-grade ductal carcinoma in situA condition in which cells that look very different from normal cells under a microscope are found in the...
high-grade lymphomaA type of lymphoma that grows and spreads quickly and has severe symptoms. Also called aggressive lymphoma...
high-grade squamous intraepithelial lesionAn area of abnormal cells that forms on the surface of certain organs, such as the cervix, vagina, vulva...
high-intensity focused ultrasound therapyA procedure in which high-energy sound waves are aimed directly at an area of abnormal cells or tissue in the...
highly active antiretroviral therapyTreatment that uses a combination of three or more drugs to treat HIV infection. Highly active antiretroviral...
high-resolution micro-ultrasoundA procedure that uses high-energy sound waves to create pictures of the prostate and surrounding tissue that...
high-risk cancerCancer that is likely to recur (come back), or spread.
high-risk HPVA group of cancer-causing human papillomaviruses (HPV). These viruses can infect the cells on the moist...
high-risk human papillomavirusA group of cancer-causing human papillomaviruses (HPV). These viruses can infect the cells on the moist...
high-selenium baker's yeastA baker’s yeast (Saccharomyces cerevisiae) containing high levels of the trace element selenium (Se) with...
high-selenium Brassica junceaBrassica juncea that has been grown in high levels of selenium. Brassica juncea is a plant of the cabbage...
high-titer RSV immune globulin RI-001A plasma-derived, polyclonal, intravenous immunoglobulin formulation (IVIG) containing standardized high...
hilarRefers to the area where nerves and blood vessels attach to an organ.
HIPAAA 1996 U.S. law that allows workers and their families to keep their health insurance when they change or...
HIPECA treatment used during surgery in which a heated solution containing anticancer drugs is infused directly...
Hirschsprung diseaseA condition in which certain nerve cells are missing from the muscle layers of part of the large intestine...
histamineA substance that has many effects in the body. It is released from some types of white blood cells during...
histamine dihydrochlorideA substance being studied in the treatment of some types of cancer and other conditions. When used together...
histiocytic neoplasmA group of rare disorders in which too many histiocytes (a type of white blood cell) build up in certain...
histiocytoid hemangiomaA rare benign (not cancer) tumor of small blood vessels surrounded by lymphocytes and eosinophils (types of...
histiocytosisA group of rare disorders in which too many histiocytes (a type of white blood cell) build up in certain...
histologic examinationThe examination of tissue specimens under a microscope.
histologic gradeA description of a tumor based on how abnormal the cancer cells and tissue look under a microscope and how...
histologyThe study of tissues and cells under a microscope.
histoneA type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help...
histone deacetylaseAn enzyme that removes a small molecule called an acetyl group from histones (proteins found in chromosomes)...
histone deacetylase inhibitorA substance that causes a chemical change that stops tumor cells from dividing. Histone deacetylase...
histone methyltransferase inhibitorA substance that blocks certain enzymes involved in gene expression and cell division. These enzymes may be...
histone-lysine N-methyltransferase EZH2 inhibitor GSK2816126A small molecule selective and S-adenosyl methionine (SAM) competitive inhibitor of histone-lysine...
histopathologyThe study of diseased cells and tissues using a microscope.
historic cohort studyA research study in which the medical records of groups of individuals who are alike in many ways but differ...
historical control subjectAn individual treated in the past and used in a comparison group when researchers analyze the results of a...
histrelin acetateA drug used under the brand name Vantas as palliative therapy for advanced prostate cancer. Histrelin acetate...
HIVThe cause of acquired immunodeficiency syndrome (AIDS). Also called human immunodeficiency virus.
HIV antibodyA substance produced by certain white blood cells in reaction to contact with the human immunodeficiency...
HIV antibody testA test to check for human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired...
HIV DNA testA test to check for human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired...
HIV negativeRefers to a person who is not infected with the human immunodeficiency virus (HIV). HIV is the virus that...
HIV positiveRefers to a person who is infected with the human immunodeficiency virus (HIV). HIV is the virus that causes...
HIV RNA testA test to check for human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired...
HIV testA test to check for human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired...
HIV window periodThe time period that starts when a person becomes infected with the human immunodeficiency virus (HIV) and...
hivesItchy, raised red areas on the skin. Hives are caused by a reaction to certain foods, drugs, infections, or...
HLAA type of molecule found on the surface of most cells in the body. HLAs play an important part in the body's...
HLA matchingA process in which blood or tissue samples are tested for human leukocyte antigens (HLAs). HLAs are molecules...
HLA-A*02:01 antigenA common cell surface marker that is part of the set of HLA antigens that make up a person’s tissue type. HLA...
HLA-A*0201-restricted TERT(572Y)/TERT(572) peptides vaccine Vx-001A peptide-based cancer vaccine consisting of two human leukocyte antigen (HLA)-A*0201 restricted 9-mer...
HLA-A*0201-restricted TRP2-gp100-EphA2-HER2 multipeptide vaccineA cancer vaccine containing four HLA-A*0201-restricted peptide epitopes with potential immunostimulatory and...
HLA-A*0201-restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccineA cancer vaccine containing three HLA-A*2402-restricted peptide epitopes with potential immunostimulatory...
HLA-A*0201-restricted VEGFR1 peptide vaccineA cancer vaccine containing an HLA-A*0201-restricted vascular endothelial growth factor receptor 1 (VEGFR1)...
HLA-A*0201-restricted VEGFR1-VEGFR2 multipeptide vaccineA cancer vaccine containing two HLA-A*0201-restricted peptide epitopes with potential immunostimulatory and...
HLA-A1, A2, B35-restricted survivin peptides/Montanide ISA-51 vaccineA peptide vaccine comprised of synthetic HLA-A1, -A2 and -B35 restricted survivin epitopes combined with the...
HLA-A1-binding MAGE-1/MAGE-3 multipeptide-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen...
HLA-A2, A3-restricted FGF-5 peptides/Montanide ISA-51 vaccineA peptide vaccine comprised of synthetic HLA-A2- and HLA-A3-binding peptides, derived from amino acid...
HLA-A*2402-restricted CDCA1-A24-56 peptide vaccineA cancer vaccine containing the HLA-A*2402-restricted peptide epitope derived from cell division associated...
HLA-A*2402-restricted CDCA1-KIF20A multipeptide vaccineA cancer vaccine containing two HLA-A*2402-restricted peptide epitopes derived from cancer-testis antigens...
HLA-A*2402-restricted KOC1-TTK-CO16-DEPDC1-MPHOSPH1 multipeptide vaccineA cancer vaccine containing five HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and...
HLA-A*2402-restricted multipeptide vaccine S-488410A cancer vaccine composed of HLA-*2402-restricted epitopic peptides derived from three cancer/testis (CT)...
HLA-A*2402-restricted URLC10 peptides vaccineA cancer vaccine containing HLA-A*2402-restricted epitope peptides URLC10 (up-regulated lung cancer 10) with...
HLA-A*2402-restricted URLC10-CDCA1-KIF20A multipeptide vaccineA cancer vaccine containing three HLA-A*2402-restricted peptide epitopes derived from cancer-testis antigens...
HLA-A*2402-restricted URLC10-CDCA1-VEGFR1-VEGFR2 multipeptide vaccineA cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and...
HLA-A*2402-restricted URLC10-KOC1-VEGFR1-VEGFR2 multipeptide vaccineA cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and...
HLA-A*2402-restricted URLC10-TTK-KOC1 multipeptide vaccineA cancer vaccine containing three HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and...
HLA-A*2402-restricted URLC10-TTK-VEGFR1-VEGFR2 multipeptide vaccineA cancer vacine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and...
HLA-A*2402-restricted VEGFR1 peptide vaccineA cancer vaccine containing the HLA-A*2402-restricted vascular endothelial growth factor receptor 1 (VEGFR1)...
HLA-A*2402-restricted VEGFR1/2 multipeptide vaccineA cancer vaccine containing two HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and...
HLA-A*2404-restricted RNF43-TOMM34-VEGFR1-VEGFR2 multipeptide vaccineA cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and...
HLA-A2-binding TYR/MART-1/gp100 multipeptide-pulsed autologous dendritic cell vaccineA cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen...
HLA-A2-restricted melanoma-specific peptides vaccine GRN-1201A cancer peptide vaccine composed of four human leukocyte antigen (HLA)-A2 (HLA-A*02)-restricted peptides...
HLA-A2-restricted synthetic glioma antigen peptides vaccineA synthetic peptide cancer vaccine consisting of HLA-A2-restricted peptides derived from glioma-associated...
HLA-DP0401/0402-restricted, MAGE-A3-reactive T cell receptor-transduced autologous T cellsHuman autologous T-lymphocytes transduced with a retroviral vector encoding a T-cell receptor (TCR) specific...
HLHA rare disorder in which histiocytes and lymphocytes (types of white blood cells) build up in organs...
hLL1A substance being studied in the treatment of multiple myeloma and several other types of cancer. It binds to...
HLOD scoreA statistical estimate of whether two genetic loci are physically near enough to each other (or “linked”) on...
HLRCCA rare, inherited disorder in which benign (not cancer) skin lesions called leiomyomas form in the smooth...
HM2/MMAE antibody-drug conjugate ALT-P7An antibody-drug conjugate (ADC) composed of the trastuzumab biobetter HM2 conjugated, in a site-specific...
HMGA1A protein that binds to the DNA and certain proteins in chromosomes. It is involved in many functions in the...
HMGB1 inhibitor SB17170An orally bioavailable prodrug of SB1703, a small molecule inhibitor of high mobility group protein B1...
HMG-CoA reductase inhibitorA substance that blocks an enzyme needed by the body to make cholesterol and lowers the amount of cholesterol...
HMR 1275A substance being studied in the treatment of several types of cancer. It stops cells from dividing and may...
HMT inhibitorA substance that blocks certain enzymes involved in gene expression and cell division. These enzymes may be...
HNPCCAn inherited disorder that increases the risk of developing colorectal cancer, endometrial cancer, ovarian...
HO/02/02A topical formulation that can be used to relieve radiation dermatitis.
Hodgkin and Reed-Sternberg cellA type of cell that appears in people with Hodgkin disease. The number of these cells increases as the...
Hodgkin diseaseA cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg...
Hodgkin lymphomaA cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg...
Hodgkin's antigens-GM-CSF-expressing cell vaccineAn allogeneic vaccine consisting of Hodgkin lymphoma cells transfected with the granulocyte...
holmium Ho 166 poly(L-lactic acid) microspheresHolmium Ho166 containing poly l-lactic acid (PLA) microspheres with potential antineoplastic actvity. Upon...
holy thistleA plant whose leaves, stems, and flowers have been used in some cultures to treat certain medical problems...
homeopathic medicineAn alternative approach to medicine based on the belief that natural substances, prepared in a special way...
homeopathyAn alternative approach to medicine based on the belief that natural substances, prepared in a special way...
homeostasisA state of balance among all the body systems needed for the body to survive and function correctly. In...
homeostaticHaving to do with homeostasis, which is a state of balance among all the body systems, needed for the body to...
homoharringtonineA drug used to treat adults with certain types of chronic myelogenous leukemia that cannot be treated with...
homologous recombination repair pathwayDescribes a process in a cell in which a group of proteins work together to repair DNA damage. Changes in the...
homozygous genotypeA term that describes having two identical versions of the same gene (one inherited from the mother and one...
honeyA sweet and viscous fluid produced by honey bees from flower nectar and other plant fluids.
honey-based nutritional supplementA nutritional supplement composed of bee-honey, produced in a special process using bees which are fed a...
honey-containing mouthwashA mouthwash containing honey with potential antimucositis activity. Upon rinsing with this mouthwash, honey...
hookahA device used to smoke a special type of tobacco that comes in different flavors. In a hookah, charcoal is...
hormonal contraceptionA type of birth control that uses hormones to prevent pregnancy. Hormonal contraceptives contain estrogen and...
hormonal therapyTreatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause)...
hormoneOne of many substances made by glands in the body. Hormones circulate in the bloodstream and control the...
hormone receptorA cell protein that binds a specific hormone. The hormone receptor may be on the surface of the cell or...
hormone receptor negativeDescribes cells that do not have a group of proteins that bind to a specific hormone. For example, some...
hormone receptor positiveDescribes cells that have a group of proteins that bind to a specific hormone. For example, some breast...
hormone receptor statusA term used to describe whether cells have proteins called hormone receptors that bind to a specific hormone...
hormone receptor testA test to measure the amount of certain proteins, called hormone receptors, in cancer tissue. Hormones can...
hormone replacement therapyTreatment with hormones to replace natural hormones when the body does not make enough. For example, hormone...
hormone responsiveIn oncology, describes cancer that responds to hormone treatment.
hormone therapyTreatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause)...
hormone treatmentTreatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause)...
hormone-refractoryIn medicine, describes a disease or condition that does not respond to treatment with hormones. Also called...
hormone-resistantIn medicine, describes a disease or condition that does not respond to treatment with hormones. Also called...
hormone-sensitive prostate cancerProstate cancer that needs androgens (male hormones) to grow and therefore stops growing when androgens are...
Horner syndromeA condition in which one side of the face is flushed, does not produce sweat, and has a constricted pupil and...
horse anti-thymocyte globulinA purified, concentrated and sterile solution of horse-derived gamma globulin obtained by the immunization of...
hospiceA program that gives special care to people who are near the end of life and have stopped treatment to cure...
hospice centerA place that provides special care for people who are near the end of life and have stopped treatment to cure...
hospitalistA medical doctor who manages and coordinates the daily medical care of patients while they are in the...
host cellA cell that is infected by a virus or another type of microorganism.
host dendritic cell vaccine-001 MSSM/BIIRA dendritic cell (DC) vaccine containing ex vivo expanded autologous DCs obtained from a patient with...
hot flashA sudden, temporary onset of body warmth, flushing, and sweating (often associated with menopause).
hot noduleWhen radioactive material is used to examine the thyroid with a scanner, nodules that collect more...
hot tumorDescribes a tumor that is likely to trigger a strong immune response. Hot tumors often have many molecules on...
hotspotIn genetics, an area of DNA that is likely to mutate (change).
Hou Gu Mi XiAn orally bioavailable dietary supplement and a formulation derived from the traditional Chinese medicine...
Hpk1 inhibitor BB3008An orally bioavailable inhibitor of the serine/threonine enzyme hematopoietic progenitor kinase 1 (Hpk1...
HPK1 inhibitor BGB-15025An orally bioavailable inhibitor of the serine/threonine enzyme hematopoietic progenitor kinase-1 (Hpk1...
Hpk1 Inhibitor BGB-26808An orally bioavailable inhibitor of the serine/threonine enzyme hematopoietic progenitor kinase 1 (Hpk1...
Hpk1 inhibitor CFI-402411An orally bioavailable inhibitor of the serine/threonine enzyme hematopoietic progenitor kinase-1 (Hpk1...
Hpk1 inhibitor FB849An orally bioavailable inhibitor of the serine/threonine enzyme hematopoietic progenitor kinase 1 (Hpk1...
HPK1 inhibitor GRC 54276An orally bioavailable small molecule inhibitor of the serine/threonine enzyme hematopoietic progenitor...
Hpk1 inhibitor PF-07265028An orally bioavailable inhibitor of the serine/threonine enzyme hematopoietic progenitor kinase 1 (Hpk1...
Hpk1 inhibitor PRJ1-3024An orally bioavailable inhibitor of the serine/threonine enzyme hematopoietic progenitor kinase-1 (Hpk1...
HPPH2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a. A drug that is used in photodynamic therapy that is...
HPRCA rare, inherited disorder that increases the risk of a type of kidney cancer called type 1 papillary kidney...
HPVA group of more than 200 common viruses. Some HPVs, called cutaneous HPVs, are transmitted by casual contact...
HPV 16A type of HPV that is transmitted sexually and causes cancers of the cervix, anus, oropharynx (the middle...
HPV 16 E6 peptides vaccine/candida albicans extractA human papillomavirus (HPV) type 16 vaccine containing four E6 peptides in combination with the extract of...
HPV 16 E6/E7-encoding arenavirus vaccine HB-202A cancer vaccine consisting of replication-attenuated arenavirus encoding the inactivated fusion protein of...
HPV 16 E7 antigen-expressing Lactobacillis casei vaccine BLS-ILB-E710cAn orally available Lactobacillis casei (L. casei)-based vaccine expressing the human papillomavirus (HPV)...
HPV 16 E7:86-93 peptide vaccineA synthetic peptide vaccine consisting of amino acids 86 through 93 (TLGIVCPI) of the viral oncoprotein human...
HPV 16/18 E6/E7 DNA vaccine pBI-11A therapeutic codon-optimized DNA vaccine encoding for the E6 and E7 proteins of human papillomavirus (HPV)...
HPV 16/18 E6/E7-encoding lentiviral vector-based vaccine Lenti-HPV-07A cancer vaccine consisting of a non-integrative lentiviral vector encoding the detoxified forms of the human...
HPV 16/18 E6/E7/HSP70 plasmid DNA prime vaccine pBI-11/HPV 16/18 E6/E7 Vaccinia boost vaccine TA-HPV PVX7A therapeutic prime/boost cancer vaccine consisting of PVX7, which is a combination of two vaccines: the...
HPV 18A type of HPV that is transmitted sexually and causes cancers of the cervix, anus, oropharynx (the middle...
HPV DNA testA laboratory test in which cells are scraped from the cervix to look for DNA of human papillomaviruses (HPV)...
HPV E1/E2 interaction inhibitor gel AP611074A topical gel composed of a human papillomavirus (HPV) E1/E2 protein:protein interaction (PPI) inhibitor with...
HPV E6/E7 DNA vaccine GX-188EA therapeutic DNA vaccine encoding the E6/E7 fusion protein of human papillomavirus (HPV) subtypes 16 and 18...
HPV E6/E7-encoding arenavirus vaccine HB-201A cancer vaccine consisting of a replication-attenuated arenavirus lymphocytic choriomeningitis virus (LCMV)...
HPV E6/E7-encoding Semliki Forest virus vaccine Vvax001A vaccine consisting of a recombinant, attenuated, replication-incompetent form of the Semliki Forest Virus...
HPV L1 virus-like particles vaccine NBP615A human papillomavirus (HPV) vaccine composed of purified virus-like particles (VLPs) comprised of major...
HPV L1 VLP vaccine V504A vaccine formulation consisting of several types of human papillomavirus (HPV)-derived noninfectious...
HPV RNA testA laboratory test in which cells are scraped from the cervix to look for RNA of the most common types of...
HPV testA laboratory test in which cells are tested for DNA or RNA from certain types of human papillomavirus (HPV)...
HPV types 16/18 E6/E7-adenoviral transduced autologous lymphocytes/alpha-galactosylceramide vaccine BVAC-CAn immunotherapeutic vaccine composed of the immunoadjuvant alpha-galactosylceramide (a-GC) and autologous...
HPV vaccineA vaccine that helps protect the body against infection with certain types of human papillomavirus (HPV). HPV...
HPV16 E6/7 mRNA vaccine BNT113A RNA-lipoplex (RNA-LIP)-based cancer vaccine containing messenger RNA (RNA) encoding for the human...
HPV-16 E7 TCR expressing T cellsA preparation of allogeneic, genetically engineered T lymphocytes transduced with a retroviral vector MSGV1...
HPV16 E7-specific HLA-A*02:01-restricted IgG1-Fc fusion protein CUE-101A fusion protein composed of a human leukocyte antigen (HLA) complex, HLA-A*0201, with a peptide epitope...
HPV16 L2/E6/E7 fusion protein vaccine TA-CINA recombinant human papillomavirus (HPV), genetically engineered fusion protein vaccine in which the three...
HPV16 RG1 VLP vaccineA monovalent chimeric human papillomavirus (HPV) virus-like particles (VLPs)-based vaccine containing the...
HPV16-E6-T27A transcription activator-like effector nucleases (TALEN)-edited plasmid targeting the human papillomavirus...
HPV16-E711-19 peptide vaccine DPX-E7A therapeutic vaccine composed of a synthetic peptide consisting of amino acids 11 through 19 of the viral...
HPV16-E7-T512A transcription activator-like effector nucleases (TALEN)-edited plasmid targeting human papillomavirus (HPV)...
HPV6/11-targeted DNA plasmid vaccine INO-3107A DNA vaccine consisting of plasmids encoding E6 and E7 genes of human papilloma virus subtype 6 (HPV-6) and...
HPV-6-targeting immunotherapeutic vaccine INO-3106A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus subtype 6 (HPV-6)...
HPV/Pap cotestA procedure in which a human papillomavirus (HPV) test and a Pap test are done at the same time to check for...
H-ras antisense oligodeoxynucleotide ISIS 2503A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation...
HRAS geneA gene that makes a protein that is involved in cell signaling pathways that control cell growth and cell...
HRR pathwayDescribes a process in a cell in which a group of proteins work together to repair DNA damage. Changes in the...
HRTTreatment with hormones to replace natural hormones when the body does not make enough. For example, HRT may...
HSD-1 inhibitor SPI-62An orally bioavailable selective inhibitor of the enzyme 11beta-hydroxysteroid dehydrogenase type 1...
HSILAn area of abnormal cells that forms on the surface of certain organs, such as the cervix, vagina, vulva...
HSPOne of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of...
Hsp70-peptide TKD/IL-2-activated autologous natural killer cellsA preparation of autologous natural killer (NK) cells that are stimulated ex vivo by a 14-mer heat shock...
Hsp90 antagonist KW-2478An agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity...
Hsp90 inhibitor AB-010An orally bioavailable nanoparticle albumin-bound inhibitor of heat shock protein 90 (Hsp90) with potential...
Hsp90 inhibitor AT13387A synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential...
Hsp90 inhibitor AUY922A derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with...
Hsp90 inhibitor BIIB028A small-molecule inhibitor of heat shock protein (Hsp) 90 with potential antineoplastic activity. Hsp90...
Hsp90 inhibitor CNF2024An orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential...
Hsp90 inhibitor debio 0932An orally active and small molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic...
Hsp90 inhibitor DS-2248An orally active and small molecule inhibitor of heat shock protein 90 (Hsp90), with potential antineoplastic...
HSP90 inhibitor HSP990An orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic...
Hsp90 inhibitor MPC-3100An orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90...
Hsp90 inhibitor MPT0B640An orally bioavailable inhibitor of heat shock protein 90 (Hsp90), with potential antineoplastic activity...
Hsp90 inhibitor NVP-BEP800An orally bioavailable inhibitor of heat shock protein 90 (Hsp90), with potential antineoplastic activity...
Hsp90 inhibitor SNX-5422 mesylateThe orally bioavailable mesylate salt of a synthetic prodrug targeting the human heat-shock protein 90...
Hsp90 inhibitor TQB3474An inhibitor of heat shock protein 90 (Hsp90), with potential antineoplastic activity. Upon administration...
Hsp90 inhibitor XL888An orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with...
HSP90 peptide vaccine AST-021pA cancer vaccine containing a peptide antigen derived from a specific protein heat shock protein 90 (HSP90)...
HSP90-targeted photosensitizer HS-201A conjugate consisting of a heat shock protein 90 (Hsp90) inhibitor connected via a linker to verteporfin, a...
HSP90-targeted SN-38 conjugate PEN-866A miniature drug conjugate composed of the irinotecan metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38)...
HSPCProstate cancer that needs androgens (male hormones) to grow and therefore stops growing when androgens are...
HspE7A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and...
HSVA type of virus that causes herpes infections and has DNA as its genetic material. There are two types of...
HSV-thymidine kinase-m2 and hGM-CSF genes-encoding GEN2A gene therapy agent composed of a vector expressing a mutated form of the herpes simplex virus thymidine...
HSV-TK-transduced donor lymphocytesA preparation of donor lymphocytes transduced with the "suicide" gene herpes simplex virus thymidine kinase...
hTERT I540/R572Y/D988Y multipeptide vaccineA peptide vaccine consisting of multiple epitopes derived from the human telomerase reverse transcriptase...
hTERT mRNA /survivin peptide-double-loaded autologous dendritic cell vaccineA cancer vaccine containing autologous dendritic cells (DCs) that are pulsed with mRNA encoding human...
hTERT multipeptide/Montanide ISA-51 VG/imiquimod GX 301A therapeutic cancer vaccine consisting of four epitopes derived from the human telomerase reverse...
hTERT vaccine V934/V935A cancer vaccine directed against human telomerase reverse transcriptase (hTERT), the catalytic subunit of...
hTERT-encoding DNA vaccine INVAC-1A DNA vaccine consisting of a plasmid encoding a modified, inactive form of the human telomerase reverse...
hTERT-LAMP mRNA-loaded autologous dendritic cell vaccine GRNVAC1A cancer vaccine containing autologous dendritic cells (DCs) that are pulsed with mRNA encoding the...
hTERT/survivin/CMV multipeptide vaccineA vaccine containing multiple peptides derived from the human telomerase reverse transcriptase (hTERT)...
hTERT/survivin/melanoma tumor cell-derived mRNA-transfected dendritic cell vaccineA cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding...
HTLV-1A type of virus that infects T cells (a type of white blood cell) and can cause leukemia and lymphoma. HTLV-1...
hu14.18-IL2 fusion proteinA recombinant protein consisting of the hu14.18 monoclonal antibody fused to the cytokine interleukin-2 (IL2)...
hu14.18-interleukin-2 fusion proteinAn anticancer drug in which hu14.18, a monoclonal antibody, is combined with interleukin-2. The monoclonal...
Hu3S193A monoclonal antibody that is being studied in the treatment of some types of cancer. Monoclonal antibodies...
huachansuA traditional Chinese medicine (TCM) containing a water soluble Bufo toad skin extract that includes the...
HuAFP31A monoclonal antibody being studied in the treatment of several types of cancer. Monoclonal antibodies are...
Huaier extract granuleAn orally bioavailable traditional Chinese medicine (TCM) composed of a granule containing an aqueous extract...
Huang LianA Chinese herb that has been used as a treatment for a variety of medical problems. It is being studied as an...
Huang QiA Chinese herbal medicine (CHM) containing the root of the perennial herbaceous plant Astragalus (Radix...
Huangqi Guizhi Wuwu decoctionA traditional Chinese medicine (TCM) composed of a decoction containing Sheng huangqi (Radix Astragali seu...
huBC1-huIL12 fusion protein AS1409An immunoconjugate consisting of the anti-tumor cytokine interleukin-12 (IL-12) fused to the tumor-targeting...
huC242-DM4A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal...
HuHMFG1A monoclonal antibody that binds to the protein MUC1, which is found on breast, ovarian, pancreatic, gastric...
HuLuc63A drug used with dexamethasone and either lenalidomide or pomalidomide to treat adults with multiple myeloma...
human acellular dermal matrixAn allograft composed of sterile, decellularized regenerative human dermal tissue matrix, with soft tissue...
human adenovirus type 5 encoding HPV-16 E6/E7 vaccine IBRX-042A cancer vaccine composed of an adenovirus type 5 (Ad5) vector that encodes for the viral oncoproteins E6 and...
human anti-CD30 CAR-expressing autologous T-lymphocytesA preparation of autologous T-lymphocytes that have been genetically modified to express a chimeric antigen...
human corticotropin-releasing factorA substance being studied in the treatment of brain cancer. It is made naturally by the hypothalamus (a part...
human EGF receptor 2A protein involved in normal cell growth. Human EGF receptor 2 may be made in larger than normal amounts by...
human embryonic stem cell-derived midbrain dopamine neuron cells MSK-DA01A preparation of midbrain dopamine neurons derived from human embryonic stem cells that could potentially be...
human epidermal growth factor receptor 2A protein involved in normal cell growth. Human epidermal growth factor receptor 2 may be made in larger than...
human epidermal growth factor receptor 2 negativeDescribes cells that have a small amount or none of a protein called HER2 on their surface. In normal cells...
human epidermal growth factor receptor 2 positiveDescribes cells that have a protein called HER2 on their surface. In normal cells, HER2 helps control cell...
human epidermal growth factor receptor 2 testA laboratory test that measures the amount of HER2 protein on cancer cells or how many copies of the HER2...
human epididymis protein 4A protein found on cells that line the lungs and reproductive organs, such as the ovaries. Human epididymis...
human gp100 plasmid DNA vaccineA vaccine consisting of a plasmid DNA encoding the human melanoma-associated antigen gp100. Upon...
human hepatitis B virus immune globulinA preparation containing immunoglobulin (Igs), mainly immunoglobulin G (IgG), against hepatitis B virus...
human herpesvirusA type of virus that causes herpes infections and has DNA as its genetic material. There are two types of...
human herpesvirus 8A type of virus that causes Kaposi sarcoma (a rare cancer in which lesions grow in the skin, lymph nodes...
human immunodeficiency virusThe cause of acquired immunodeficiency syndrome (AIDS). Also called HIV.
human immunoglobulin GA sterile preparation of purified immunoglobulin G (IgG) derived from large pools of human plasma. Upon...
human lactoferrin peptide hLF1-11A synthetic peptide corresponding to the first 11 N-terminal amino acids of human lactoferrin (hLF1-11) with...
human leukocyte antigenA type of molecule found on the surface of most cells in the body. Human leukocyte antigens play an important...
human leukocyte antigen matchingA process in which blood or tissue samples are tested for human leukocyte antigens (HLAs). HLAs are molecules...
human lymphocyte antigenA type of molecule found on the surface of most cells in the body. Human lymphocyte antigens play an...

632 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.