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Human epidermal growth factor receptor 2 negative

Term · Oncology and biomedicine · MLC-T-ONC-004004

Describes cells that have a small amount or none of a protein called HER2 on their surface. In normal cells, HER2 helps control cell growth. Cancer cells that are human epidermal growth factor receptor 2 negative may grow more slowly and are less likely to recur (come back) or spread to other parts of the body than cancer cells that have a large amount of HER2 on their surface. Checking to see if a cancer is human epidermal growth factor receptor 2 negative may help plan treatment. Cancers that may be human epidermal growth factor receptor 2 negative include breast, bladder, ovarian, pancreatic, and stomach cancers. Also called HER2 negative.

Table 1. Record
IdentifierMLC-T-ONC-004004
FieldOncology and biomedicine
SynonymsHER2 negative
ReferencesNCI Dictionary of Cancer Terms
Record as JSON
{
  "id": "MLC-T-ONC-004004",
  "term": "Human epidermal growth factor receptor 2 negative",
  "field": "Oncology and biomedicine",
  "definition": "Describes cells that have a small amount or none of a protein called HER2 on their surface. In normal cells, HER2 helps control cell growth. Cancer cells that are human epidermal growth factor receptor 2 negative may grow more slowly and are less likely to recur (come back) or spread to other parts of the body than cancer cells that have a large amount of HER2 on their surface. Checking to see if a cancer is human epidermal growth factor receptor 2 negative may help plan treatment. Cancers that may be human epidermal growth factor receptor 2 negative include breast, bladder, ovarian, pancreatic, and stomach cancers. Also called HER2 negative.",
  "synonyms": [
    "HER2 negative"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/human-epidermal-growth-factor-receptor-2-negative/"
}

Record 8,732 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.