High-grade squamous intraepithelial lesion

{
  "id": "MLC-T-ONC-003890",
  "term": "High-grade squamous intraepithelial lesion",
  "field": "Oncology and biomedicine",
  "definition": "An area of abnormal cells that forms on the surface of certain organs, such as the cervix, vagina, vulva, anus, and esophagus. High-grade squamous intraepithelial lesions look somewhat to very abnormal when looked at under a microscope. They are usually caused by chronic infection with certain types of human papillomavirus (HPV) and are found when a Pap test or biopsy is done. If not treated, these abnormal cells may become cancer and spread into nearby tissue. A high-grade squamous intraepithelial lesion is sometimes called moderate or severe dysplasia. Also called HSIL.",
  "synonyms": [
    "HSIL"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/high-grade-squamous-intraepithelial-lesion/"
}