MLchartDataset catalogue

HLA-A*2402-restricted multipeptide vaccine S-488410

Term · Oncology and biomedicine · MLC-T-ONC-014140

A cancer vaccine composed of HLA-*2402-restricted epitopic peptides derived from three cancer/testis (CT) antigens, with potential antineoplastic activity. Upon subcutaneous administration, HLA-A*2402-restricted multipeptide vaccine S-488410 may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing these CT antigens. CT antigens, normally expressed only in germ cells of the testis, are overexpressed in a wide variety of human cancers.

Table 1. Record
IdentifierMLC-T-ONC-014140
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014140",
  "term": "HLA-A*2402-restricted multipeptide vaccine S-488410",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine composed of HLA-*2402-restricted epitopic peptides derived from three cancer/testis (CT) antigens, with potential antineoplastic activity. Upon subcutaneous administration, HLA-A*2402-restricted multipeptide vaccine S-488410 may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing these CT antigens. CT antigens, normally expressed only in germ cells of the testis, are overexpressed in a wide variety of human cancers.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/hla-a-2402-restricted-multipeptide-vaccine-s-488410/"
}

Record 8,561 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.