HER2 inhibitor ZN-A-1041

{
  "id": "MLC-T-ONC-014094",
  "term": "HER2 inhibitor ZN-A-1041",
  "field": "Oncology and biomedicine",
  "definition": "An orally bioavailable inhibitor of the receptor tyrosine kinase human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential antineoplastic activity. Upon oral administration, HER2 inhibitor ZN-A-1041 selectively binds to and inhibits the activity of HER2. This prevents HER2-mediated signaling and may lead to cell death in HER2-expressing tumor cells. HER2, a receptor tyrosine kinase overexpressed on a variety of tumor cell types, plays an important role in tumor cell proliferation and tumor vascularization.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/her2-inhibitor-zn-a-1041/"
}