HPV6/11-targeted DNA plasmid vaccine INO-3107

{
  "id": "MLC-T-ONC-014195",
  "term": "HPV6/11-targeted DNA plasmid vaccine INO-3107",
  "field": "Oncology and biomedicine",
  "definition": "A DNA vaccine consisting of plasmids encoding E6 and E7 genes of human papilloma virus subtype 6 (HPV-6) and 11 (HPV-11), with potential immunostimulating and antineoplastic activities. Upon administration via intramuscular electroporation, the HPV-6/11-targeted DNA plasmid vaccine INO-3107 expresses the HPV-6/11 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing HPV6 and/or HPV11 E6 and E7 proteins, resulting in tumor cell lysis. HPV-6/11 infections are associated with aerodigestive malignancies.",
  "synonyms": [
    "HPV-6/11-targeting immunotherapeutic vaccine INO-3107",
    "HPV6/11-targeted DNA plasmid immunotherapeutic INO-3107"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/hpv6-11-targeted-dna-plasmid-vaccine-ino-3107/"
}