HIF2a RNAi ARO-HIF2

{
  "id": "MLC-T-ONC-014119",
  "term": "HIF2a RNAi ARO-HIF2",
  "field": "Oncology and biomedicine",
  "definition": "An RNA interference (RNAi) targeting hypoxia-inducible factor 2alpha (HIF-2a), with potential antineoplastic activity. Upon administration of HIF2a RNAi ARO-HIF2, the agent binds to and neutralizes mRNA HIF2a, thereby preventing the production of HIF2a. This may lead to an inhibition of tumor cell proliferation. HIF2a, overexpressed in certain cell types, plays a key role in proliferation, progression and metastasis of tumors.",
  "synonyms": [
    "RNA interference therapeutic ARO-HIF2",
    "targeted RNAi molecule ARO-HIF2",
    "TRiM ARO-HIF2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/hif2a-rnai-aro-hif2/"
}