HLA-A2-restricted melanoma-specific peptides vaccine GRN-1201

{
  "id": "MLC-T-ONC-014151",
  "term": "HLA-A2-restricted melanoma-specific peptides vaccine GRN-1201",
  "field": "Oncology and biomedicine",
  "definition": "A cancer peptide vaccine composed of four human leukocyte antigen (HLA)-A2 (HLA-A*02)-restricted peptides derived from four specific and separate tumor-associated antigens (TAAs) expressed by melanoma cells, with potential antineoplastic activity. Upon administration of the HLA-A2-restricted melanoma-specific peptides vaccine, the melanoma specific antigens in the vaccine activate the immune system to exert a cytotoxic T-lymphocyte (CTL) response against the HLA-A2-positive melanoma cells.",
  "synonyms": [
    "cancer vaccine GRN-1201",
    "peptide vaccine GRN-1201",
    "peptide cancer vaccine GRN-1201"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/hla-a2-restricted-melanoma-specific-peptides-vaccine-grn-1201/"
}