Hematoporphyrin derivative

{
  "id": "MLC-T-ONC-003778",
  "term": "Hematoporphyrin derivative",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used in photodynamic therapy that is absorbed by tumor cells. When exposed to light, it becomes active and kills the cancer cells.",
    "A complex mixture of monomeric and aggregated porphyrins with photosensitizing activity. Upon systemic administration, hematoporphyrin derivatives accumulate in tumor cells and, once activated by red laser light (630 nm), in the presence of oxygen, produce singlet oxygen and other reactive oxygen radicals, resulting in local radical-mediated tumor cell death."
  ],
  "abbreviation": "HPD",
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/hematoporphyrin-derivative/"
}