Temoporfin
Term · Oncology and biomedicine · MLC-T-ONC-008583
An anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called photosensitizing agents.
A synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size.
| Identifier | MLC-T-ONC-008583 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | mTHPC |
| Synonyms | m-tetrahydroxyphenyl-chlorin |
| References | NCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-008583",
"term": "Temoporfin",
"field": "Oncology and biomedicine",
"definitions": [
"An anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called photosensitizing agents.",
"A synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size."
],
"abbreviation": "mTHPC",
"synonyms": [
"m-tetrahydroxyphenyl-chlorin"
],
"references": [
"NCI Dictionary of Cancer Terms",
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/temoporfin/"
}
Record 16,129 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.