MLchartDataset catalogue

Temoporfin

Term · Oncology and biomedicine · MLC-T-ONC-008583

  1. An anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called photosensitizing agents.

  2. A synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size.

Table 1. Record
IdentifierMLC-T-ONC-008583
FieldOncology and biomedicine
AbbreviationmTHPC
Synonymsm-tetrahydroxyphenyl-chlorin
ReferencesNCI Dictionary of Cancer Terms; National Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-008583",
  "term": "Temoporfin",
  "field": "Oncology and biomedicine",
  "definitions": [
    "An anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called photosensitizing agents.",
    "A synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size."
  ],
  "abbreviation": "mTHPC",
  "synonyms": [
    "m-tetrahydroxyphenyl-chlorin"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/temoporfin/"
}

Record 16,129 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.