Hexaminolevulinate
Term · Oncology and biomedicine · MLC-T-ONC-014116
The hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties. As a precursor of photoactive porphorins, hexaminolevulinate induces the endogenous production of the photosensitizer protoporphyrin IX (PPIX) which accumulates selectively in tumor tissue. When exposed to specific wavelengths of light, PPIX is activated and, depending on the wavelength and/or intensity of light, either fluoresces, thereby allowing tumor imaging, or induces tumor cell apoptosis.
| Identifier | MLC-T-ONC-014116 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | HAL |
| Synonyms | hexyl 5-aminolevulinate; P-1206 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-014116",
"term": "Hexaminolevulinate",
"field": "Oncology and biomedicine",
"definition": "The hexyl ester of 5-aminolevulinic acid (ALA) with photodynamic properties. As a precursor of photoactive porphorins, hexaminolevulinate induces the endogenous production of the photosensitizer protoporphyrin IX (PPIX) which accumulates selectively in tumor tissue. When exposed to specific wavelengths of light, PPIX is activated and, depending on the wavelength and/or intensity of light, either fluoresces, thereby allowing tumor imaging, or induces tumor cell apoptosis.",
"abbreviation": "HAL",
"synonyms": [
"hexyl 5-aminolevulinate",
"P-1206"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/hexaminolevulinate/"
}
Record 8,476 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.