CDK7 inhibitor SY-1365

{
  "id": "MLC-T-ONC-012473",
  "term": "CDK7 inhibitor SY-1365",
  "field": "Oncology and biomedicine",
  "definition": "A selective inhibitor of cyclin-dependent kinase 7 (CDK7), with potential antineoplastic activity. Upon administration, SY-1365 binds to and inhibits CDK7, thereby inhibiting CDK7-mediated signal transduction pathways. This inhibits cell growth of CDK7-overexpressing tumor cells. CDK7, a serine/threonine kinase, plays a key role in cell proliferation; CDK7 is overexpressed in a variety of tumor cell types.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cdk7-inhibitor-sy-1365/"
}