chimeric antigen receptor T-cell therapy

{
  "id": "MLC-T-ONC-001677",
  "term": "chimeric antigen receptor T-cell therapy",
  "field": "Oncology and biomedicine",
  "definition": "A type of treatment in which a patient's T cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells. T cells are taken from a patient’s blood. Then the gene for a special receptor that binds to a certain protein on the patient’s cancer cells is added to the T cells in the laboratory. The special receptor is called a chimeric antigen receptor (CAR). Large numbers of the CAR T cells are grown in the laboratory and given to the patient by infusion. Chimeric antigen receptor T-cell therapy is used to treat certain blood cancers, and it is being studied in the treatment of other types of cancer. Also called CAR T-cell therapy.",
  "synonyms": [
    "CAR T-cell therapy"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/chimeric-antigen-receptor-t-cell-therapy/"
}